Biomaterials in cardiovascular research: applications and clinical implications
SK Jaganathan, E Supriyanto… - BioMed research …, 2014 - Wiley Online Library
Cardiovascular biomaterials (CB) dominate the category of biomaterials based on the
demand and investments in this field. This review article classifies the CB into three major …
demand and investments in this field. This review article classifies the CB into three major …
Patching the heart: cardiac repair from within and outside
Transplantation of engineered tissue patches containing either progenitor cells or
cardiomyocytes for cardiac repair is emerging as an exciting treatment option for patients …
cardiomyocytes for cardiac repair is emerging as an exciting treatment option for patients …
Capturing cardiogenesis in gastruloids
Organoids are powerful models for studying tissue development, physiology, and disease.
However, current culture systems disrupt the inductive tissue-tissue interactions needed for …
However, current culture systems disrupt the inductive tissue-tissue interactions needed for …
Exosomes/microvesicles from induced pluripotent stem cells deliver cardioprotective miRNAs and prevent cardiomyocyte apoptosis in the ischemic myocardium
Y Wang, L Zhang, Y Li, L Chen, X Wang, W Guo… - International journal of …, 2015 - Elsevier
Background/objectives Induced pluripotent stem cells (iPS) exhibit enhanced survival and
proliferation in ischemic tissues. However, the therapeutic application of iPS cells is limited …
proliferation in ischemic tissues. However, the therapeutic application of iPS cells is limited …
[HTML][HTML] Thymosin β4 increases cardiac cell proliferation, cell engraftment, and the reparative potency of human induced-pluripotent stem cell-derived cardiomyocytes …
SH Tan, SJ Loo, Y Gao, ZH Tao, LP Su, CX Wang… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Previous studies have shown that human embryonic stem cell-derived
cardiomyocytes improved myocardial recovery when administered to infarcted pig and non …
cardiomyocytes improved myocardial recovery when administered to infarcted pig and non …
Overcoming the roadblocks to cardiac cell therapy using tissue engineering
Transplantations of various stem cells or their progeny have repeatedly improved cardiac
performance in animal models of myocardial injury; however, the benefits observed in …
performance in animal models of myocardial injury; however, the benefits observed in …
Functional effects of a tissue-engineered cardiac patch from human induced pluripotent stem cell-derived cardiomyocytes in a rat infarct model
JS Wendel, L Ye, R Tao, J Zhang… - Stem cells …, 2015 - academic.oup.com
A tissue-engineered cardiac patch provides a method to deliver cardiomyoctes to the injured
myocardium with high cell retention and large, controlled infarct coverage, enhancing the …
myocardium with high cell retention and large, controlled infarct coverage, enhancing the …
Cardiac fibroblasts and myocardial regeneration
The billions of cardiomyocytes lost to acute myocardial infarction (MI) cannot be replaced by
the limited regenerative capacity of adult mammalian hearts, and despite decades of …
the limited regenerative capacity of adult mammalian hearts, and despite decades of …
Cardiac differentiation of bone-marrow-resident c-kit+ stem cells by L-carnitine increases through secretion of VEGF, IL6, IGF-1, and TGF-β as clinical agents in …
The idea of regenerating lost myocardium via cell-based therapies remains as highly
considerable. C-kit+ stem/progenitor cells are represented to be suitable candidates for …
considerable. C-kit+ stem/progenitor cells are represented to be suitable candidates for …
Cryopreservation of human iPS cell aggregates in a DMSO-free solution—an optimization and comparative study
Human induced pluripotent stem cells (hiPSCs) are an important cell source for regenerative
medicine products. Effective methods of preservation are critical to their clinical and …
medicine products. Effective methods of preservation are critical to their clinical and …