The morbidity and mortality from cardiovascular diseases (CVD) remain high. Metabolic
diseases such as obesity, hyperlipidemia, diabetes mellitus (DM), non-alcoholic fatty liver …

Preconditioning, postconditioning, and remote conditioning of the myocardium enhance the
ability of the heart to withstand a prolonged ischemia/reperfusion insult and the potential to …

Objective The purpose of this article is to review and integrate the available literature in
different fields to gain a better understanding of the basic physiology and optimize vascular …

In this review, we describe key signaling pathways regulating potassium channels present in
the inner mitochondrial membrane. The signaling cascades covered here include …

How to provide effective prevention and treatment of myocardial ischemia/reperfusion (I/R)
injury and study of the mechanism underlying I/R injury are hotspots of current research …

Background In the presence of comorbidities the effectiveness of many cardioprotective
strategies is blunted. The goal of this study was to assess in a hypertensive rat model if the …

A number of clinical trials have shown that a high loading dose of atorvastatin (Ator) within
24 h before percutaneous coronary intervention (PCI) exerts protective effects on the …

The aim of this study was to examine the effects of GSK‐3β inhibitors compared with PRE
and POS in spontaneously hypertensive rats (SHR). Isolated hearts were submitted to the …

Objectives To evaluate the efficiency of isoflurane-induced anesthetic preconditioning and
the role of mitochondrial manganese superoxide dismutase (MnSOD) in hypertensive …

Our aim was to assess the action of cyclosporine-A (CsA) against reperfusion injury in
spontaneously hypertensive rats (SHR) compared to the effects of ischemic pre-(IP) and …