Macrophages play an important role in a wide variety of physiologic and pathologic
processes. Plasticity and functional polarization are hallmarks of macrophages …

The ongoing worldwide increase in life expectancy portends a rising prevalence of age-
related cardiovascular (CV) diseases in the coming decades that demands a deeper …

Recent advances in human genetics, together with a large body of epidemiologic,
preclinical, and clinical trial results, provide strong support for a causal association between …

Obesity is a heterogeneous disease with different degrees of cardiovascular (CV) and
metabolic manifestations. Certain ectopic fat depots may contribute to obesity-related CV …

The continued increase in global life expectancy predicts a rising prevalence of age-related
cerebral small vessel diseases (CSVD), which requires a better understanding of the …

Neutrophils are the most abundant circulating leucocytes in healthy humans. These cells are
central players during acute inflammatory responses, although a growing body of evidence …

Embraced with apolipoproteins (Apo) B and Apo E, triglyceride-enriched very-low-density
lipoprotein (VLDL) is secreted by the liver into circulation, mainly during post-meal hours …

Cardiovascular disease is the leading cause of mortality worldwide, and atherosclerosis the
principal factor underlying cardiovascular events. Atherosclerosis is a chronic inflammatory …

Atherosclerosis is a chronic progressive inflammation course, which could induce life‐
threatening diseases such as stroke and myocardial infarction. Optimal medical treatments …

Cardiovascular diseases, the notorious killer, are mainly caused by atherosclerosis (AS)
characterized by lipids, cholesterol, and iron overload in plaques. Macrophages are effector …