The emergence of antibiotic-resistant bacterial strains is a source of public health concern
across the globe. As the discovery of new conventional antibiotics has stalled significantly …

A main challenge in the development of biosensing devices for the identification and
quantification of nucleic acids is to avoid the amplification of the genetic material from the …

With the increasing global threat of antibiotic resistance, there is an urgent need to develop
new effective therapies to tackle antibiotic-resistant bacterial infections. Bacteriophage …

Bacteria have developed different mechanisms to defend against phages, such as
preventing phages from being adsorbed on the surface of host bacteria; through the …

In this review, we describe a path for translation of gene editing into therapy for cystic fibrosis
(CF). Cystic fibrosis results from mutations in the CFTR gene, with one allele predominant in …

Recently, CRISPR-Cas system-based assays for bacterial detection have been developed.
The aim of this scoping review is to map existing evidence on the utilization of CRISPR-Cas …

Regulatory RNAs, present in many bacterial genomes and particularly in pathogenic
bacteria such as Staphylococcus aureus, control the expression of genes encoding …

The advances in synthetic biology bring exciting new opportunities to reprogram
microorganisms with novel functionalities for environmental applications. For real‐world …

New CRISPR-based genome editing technologies are developed to continually drive
advances in life sciences, which, however, are predominantly derived from systems of Type …

While phages hold promise as an antibiotic alternative, they encounter significant
challenges in combating bacterial infections, primarily due to the emergence of phage …