Personalised virtual brain models in epilepsy
Individuals with drug-resistant focal epilepsy are candidates for surgical treatment as a
curative option. Before surgery can take place, the patient must have a presurgical …
curative option. Before surgery can take place, the patient must have a presurgical …
Guidelines for the use of flow cytometry and cell sorting in immunological studies
A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …
performing flow cytometry experiments and includes comprehensive sections describing …
Upper cortical layer–driven network impairment in schizophrenia
Schizophrenia is one of the most widespread and complex mental disorders. To
characterize the impact of schizophrenia, we performed single-nucleus RNA sequencing …
characterize the impact of schizophrenia, we performed single-nucleus RNA sequencing …
[HTML][HTML] Structural network alterations in focal and generalized epilepsy assessed in a worldwide ENIGMA study follow axes of epilepsy risk gene expression
Epilepsy is associated with genetic risk factors and cortico-subcortical network alterations,
but associations between neurobiological mechanisms and macroscale connectomics …
but associations between neurobiological mechanisms and macroscale connectomics …
[HTML][HTML] A comparison of anatomic and cellular transcriptome structures across 40 human brain diseases
Genes associated with risk for brain disease exhibit characteristic expression patterns that
reflect both anatomical and cell type relationships. Brain-wide transcriptomic patterns of …
reflect both anatomical and cell type relationships. Brain-wide transcriptomic patterns of …
Operative list of genes associated with autism and neurodevelopmental disorders based on database review
CS Leblond, TL Le, S Malesys, F Cliquet… - Molecular and Cellular …, 2021 - Elsevier
The genetics of neurodevelopmental disorders (NDD) has made tremendous progress
during the last few decades with the identification of more than 1,500 genes associated with …
during the last few decades with the identification of more than 1,500 genes associated with …
[HTML][HTML] Neurodevelopmental disorders—high-resolution rethinking of disease modeling
K Khodosevich, CM Sellgren - Molecular Psychiatry, 2023 - nature.com
Neurodevelopmental disorders arise due to various risk factors that can perturb different
stages of brain development, and a combinatorial impact of these risk factors programs the …
stages of brain development, and a combinatorial impact of these risk factors programs the …
[HTML][HTML] GluN3A excitatory glycine receptors control adult cortical and amygdalar circuits
S Bossi, D Dhanasobhon, GCR Ellis-Davies, J Frontera… - Neuron, 2022 - cell.com
GluN3A is an atypical glycine-binding subunit of NMDA receptors (NMDARs) whose actions
in the brain are mostly unknown. Here, we show that the expression of GluN3A subunits …
in the brain are mostly unknown. Here, we show that the expression of GluN3A subunits …
Firing patterns in a fractional-order FithzHugh–Nagumo neuron model
Z Yao, K Sun, S He - Nonlinear Dynamics, 2022 - Springer
Various neuron models and circuits have been developed to explore how neurons detect
and encode different stimuli. However, relevant researches failed to consider edge effects …
and encode different stimuli. However, relevant researches failed to consider edge effects …
Excitatory GluN1/GluN3A glycine receptors (eGlyRs) in brain signaling
S Bossi, L Pizzamiglio, P Paoletti - Trends in Neurosciences, 2023 - cell.com
GluN3A is a glycine-binding subunit belonging to the NMDA receptor (NMDAR) family that
can assemble with GluN1 subunits to form unconventional NMDARs insensitive to glutamate …
can assemble with GluN1 subunits to form unconventional NMDARs insensitive to glutamate …