Cholesterol plays a strategic role in liposome composition; however, the quantity used to
achieve an appropriate formulation has not been yet clarified. Therefore, by screening …

Proteins of the mammalian target of rapamycin (mTOR) signaling axis are overexpressed or
mutated in cancers. However, clinical inhibition of mTOR signaling as a therapeutic strategy …

Liposomes have become an attractive alternative to encapsulate carotenoids to improve
their solubility, stability and bioavailability. The interaction mechanism of carotenoid with …

The major component in green tea polyphenols, epigallocatechin-3-gallate (EGCG), has
been demonstrated to prevent carcinogenesis. To improve the effectiveness of EGCG …

Restenosis remains the main reason for treatment failure of arterial disease. Sirolimus (SIR)
as a potent anti-proliferative agent is believed to prevent the phenomenon. The application …

Purpose: The aim of this study was to develop and characterize a liposomal product
containing sirolimus to be administered subconjunctivally for the treatment of nonresponsive …

Docetaxel (DTX) is a non-selective antineoplastic agent with low solubility and a series of
side effects. The technology of pH-sensitive and anti-epidermal growth factor receptor (anti …

The formation of stable unilamellar vesicles which hold great potential for biological as well
as biomedical applications has been reported in the aqueous mixed solution of a surface …

Characterization studies of 1-butyl-3-methyl-imidazolium bis (2-ethylhexyl) sulfosuccinate
vesicles at different pH values have been carried out by using liquid surface tension …

Liposomes show promise as biolubricants for damaged cartilage, but their small size results
in low joint and cartilage retention. We developed a zinc ion-based liposomal drug delivery …