Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis

MR Aburto, JF Cryan - Nature Reviews Gastroenterology & Hepatology, 2024 - nature.com
Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

[HTML][HTML] The gut-brain vascular axis in neuroinflammation

S Carloni, M Rescigno - Seminars in immunology, 2023 - Elsevier
The multifaceted microbiota characterizing our gut plays a crucial role in maintaining
immune, metabolic and tissue homeostasis of the intestine as well as of distal organs …

Gut microbiota regulates blood‐cerebrospinal fluid barrier function and Aβ pathology

J Xie, A Bruggeman, C De Nolf… - The EMBO …, 2023 - embopress.org
Accumulating evidence indicates that gut microbiota dysbiosis is associated with increased
blood–brain barrier (BBB) permeability and contributes to Alzheimer's disease (AD) …

Novel hypothesis and therapeutic interventions for irritable bowel syndrome: interplay between metal dyshomeostasis, gastrointestinal dysfunction, and …

Y Nakagawa, S Yamada - Molecular and Cellular Biochemistry, 2024 - Springer
Irritable bowel syndrome is a gastrointestinal disorder due to multiple pathologies. While
patients with this condition experience anxiety and depressed mood more frequently than …

[HTML][HTML] Biomimetic nanocarriers harnessing microbial metabolites usher the path for brain disease therapy

Y Gong, Z Liu, P Zhou, J Li, YB Miao - Nano TransMed, 2023 - Elsevier
The gastrointestinal system, often regarded as the'second brain of humanity,'maintains a
profound connection with the cerebral realm. Unlocking the intricate metabolic pathways of …

Short-Chain Fatty Acids and Human Health: From Metabolic Pathways to Current Therapeutic Implications

S Facchin, L Bertin, E Bonazzi, G Lorenzon… - Life, 2024 - mdpi.com
The gastrointestinal tract is home to trillions of diverse microorganisms collectively known as
the gut microbiota, which play a pivotal role in breaking down undigested foods, such as …

[HTML][HTML] Propionic Acid Impact on Multiple Sclerosis: Evidence and Challenges

L Lorefice, M Zoledziewska - Nutrients, 2024 - mdpi.com
Accumulating evidence suggests that multiple sclerosis (MS) is an environmentally
influenced disorder with contributions from life-time exposure to factors including Epstein …

The Power of Psychobiotics in Depression: A Modern Approach through the Microbiota–Gut–Brain Axis: A Literature Review

A Dziedzic, K Maciak, K Bliźniewska-Kowalska… - Nutrients, 2024 - mdpi.com
The microbiota–gut–brain (MGB) axis is a complex communication network linking the gut,
microbiota, and brain, influencing various aspects of health and disease. Dysbiosis, a …

The Role of the Intestinal Flora and Its Derivatives in Neurocognitive Disorders: A Narrative Review from Surgical Perspective

J Huang, TS Qin, Y Bo, YJ Li, RS Liu, Y Yu, XD Li… - Molecular …, 2024 - Springer
Perioperative neurocognitive dysfunction is a significant concern for population health,
impacting postoperative recovery and increasing the financial burden on patients. With an …

Distinct dendritic morphological changes in the nucleus accumbens of microbiota-deficient male mice

R Garcia-Cabrerizo, MF Viola, P Luczynski, G Clarke… - bioRxiv, 2024 - biorxiv.org
The gut microbiota has been shown to be an important regulator of brain and behaviour.
Germ-free rodents are a key model to study the microbiome-gut-brain axis to reveal the …