[HTML][HTML] Mitochondrial-related microRNAs and their roles in cellular senescence
L Luo, X An, Y Xiao, X Sun, S Li, Y Wang… - Frontiers in …, 2024 - frontiersin.org
Aging is a natural aspect of mammalian life. Although cellular mortality is inevitable, various
diseases can hasten the aging process, resulting in abnormal or premature senescence. As …
diseases can hasten the aging process, resulting in abnormal or premature senescence. As …
CGG repeats trigger translational frameshifts that generate aggregation-prone chimeric proteins
SE Wright, CM Rodriguez, J Monroe, J Xing… - Nucleic acids …, 2022 - academic.oup.com
CGG repeat expansions in the FMR1 5'UTR cause the neurodegenerative disease Fragile X-
associated tremor/ataxia syndrome (FXTAS). These repeats form stable RNA secondary …
associated tremor/ataxia syndrome (FXTAS). These repeats form stable RNA secondary …
hsa-miR-320a mediated exosome release under PD stress conditions rescue mitochondrial ROS and cell death in the recipient neuronal and glial cells
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by
dopaminergic neuronal cell death. Emerging evidence suggest exosomes as a crucial …
dopaminergic neuronal cell death. Emerging evidence suggest exosomes as a crucial …
[HTML][HTML] Guidelines for mitochondrial RNA analysis
A Jusic, Z Erpapazoglou, LT Dalgaard… - … Therapy-Nucleic Acids, 2024 - cell.com
Mitochondria are the energy-producing organelles of mammalian cells with critical
involvement in metabolism and signaling. Studying their regulation in pathological …
involvement in metabolism and signaling. Studying their regulation in pathological …
TNF-α induced NF-κB mediated LYRM7 expression modulates the tumor growth and metastatic ability in breast cancer
Tumor microenvironment (TME) of solid tumors including breast cancer is complex and
contains a distinct cytokine pattern including TNF-α, which determines the progression and …
contains a distinct cytokine pattern including TNF-α, which determines the progression and …
[HTML][HTML] Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation
Background Women who carry a premutation allele of the FMR1 gene are at increased
vulnerability to an array of age-related symptoms and disorders, including age-related …
vulnerability to an array of age-related symptoms and disorders, including age-related …
[HTML][HTML] Mitochondrial microRNAs: New Emerging Players in Vascular Senescence and Atherosclerotic Cardiovascular Disease
P Canale, A Borghini - International Journal of Molecular Sciences, 2024 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs that play an important role by controlling
gene expression in the cytoplasm in almost all biological pathways. Recently, scientists …
gene expression in the cytoplasm in almost all biological pathways. Recently, scientists …
[HTML][HTML] Molecular pathogenesis and peripheral monitoring of adult fragile X-associated syndromes
LM Valor, JC Morales, I Hervás-Corpión… - International Journal of …, 2021 - mdpi.com
Abnormal trinucleotide expansions cause rare disorders that compromise quality of life and,
in some cases, lifespan. In particular, the expansions of the CGG-repeats stretch at the 5' …
in some cases, lifespan. In particular, the expansions of the CGG-repeats stretch at the 5' …
Social Communication Delay in an Unbiased Sample of Preschoolers With the FMR1 Premutation
J Klusek, E Will, T Christensen, K Caravella… - Journal of Speech …, 2024 - ASHA
Purpose: The Fragile X Messenger Ribonucleoprotein-1 (FMR1) premutation (FXpm) is a
genetic variant that is common in the general population and is associated with health …
genetic variant that is common in the general population and is associated with health …
Enhanced translocation of TRIM32 to mitochondria sensitizes dopaminergic neuronal cells to apoptosis during stress conditions in Parkinson's disease
S Goyani, A Shinde, S Shukla, MV Saranga… - The FEBS …, 2024 - Wiley Online Library
Parkinson's disease (PD) is a chronic neurodegenerative disease characterized by
progressive loss of dopamine‐producing neurons from the substantia nigra region of the …
progressive loss of dopamine‐producing neurons from the substantia nigra region of the …