Cytomegalovirus infection and inflammation in developing brain

F Krstanović, WJ Britt, S Jonjić, I Brizić - Viruses, 2021 - mdpi.com
Human cytomegalovirus (HCMV) is a highly prevalent herpesvirus that can cause severe
disease in immunocompromised individuals and immunologically immature fetuses and …

A review of murine cytomegalovirus as a model for human cytomegalovirus disease—do mice lie?

MA Fisher, ML Lloyd - International journal of molecular sciences, 2020 - mdpi.com
Since murine cytomegalovirus (MCMV) was first described in 1954, it has been used to
model human cytomegalovirus (HCMV) diseases. MCMV is a natural pathogen of mice that …

Electrochemical detection of a single cytomegalovirus at an ultramicroelectrode and its antibody anchoring

JE Dick, AT Hilterbrand, A Boika… - Proceedings of the …, 2015 - National Acad Sciences
We report observations of stochastic collisions of murine cytomegalovirus (MCMV) on
ultramicroelectrodes (UMEs), extending the observation of discrete collision events on …

Protective capacity of neutralizing and non-neutralizing antibodies against glycoprotein B of cytomegalovirus

A Bootz, A Karbach, J Spindler, B Kropff… - PLoS …, 2017 - journals.plos.org
Human cytomegalovirus (HCMV) is an important, ubiquitous pathogen that causes severe
clinical disease in immunocompromised individuals, such as organ transplant recipients and …

B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies

S Pötzsch, N Spindler, AK Wiegers, T Fisch… - PLoS …, 2011 - journals.plos.org
Human cytomegalovirus (HCMV), a herpesvirus, is a ubiquitously distributed pathogen that
causes severe disease in immunosuppressed patients and infected newborns. Efforts are …

Early primary cytomegalovirus infection in pregnancy: maternal hyperimmunoglobulin therapy improves outcomes among infants at 1 year of age

S Visentin, R Manara, L Milanese… - Clinical infectious …, 2012 - academic.oup.com
Background. Primary cytomegalovirus (CMV) infection during pregnancy is the leading
infectious cause of congenital neurological disabilities. Early CMV infection carries a higher …

Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody

S Chandramouli, C Ciferri, PA Nikitin, S Caló… - Nature …, 2015 - nature.com
Human cytomegalovirus (HCMV) poses a significant threat to immunocompromised
individuals and neonates infected in utero. Glycoprotein B (gB), the herpesvirus fusion …

Perinatal murine cytomegalovirus infection reshapes the transcriptional profile and functionality of NK cells

C Rožmanić, B Lisnić, M Pribanić Matešić… - Nature …, 2023 - nature.com
Infections in early life can elicit substantially different immune responses and pathogenesis
than infections in adulthood. Here, we investigate the consequences of murine …

Immunoglobulin therapy of fetal cytomegalovirus infection occurring in the first half of pregnancy—a case-control study of the outcome in children

G Nigro, SP Adler, G Parruti… - Journal of Infectious …, 2012 - academic.oup.com
Background. Primary cytomegalovirus (CMV) infection early in gestation causes severe
disease. Methods. Case patients were 32 congenitally infected children aged 1–5 years who …

Human cytomegalovirus compromises development of cerebral organoids

RM Brown, PSJB Rana, HK Jaeger, JM O'Dowd… - Journal of …, 2019 - Am Soc Microbiol
Congenital human cytomegalovirus (HCMV) infection causes a broad spectrum of central
and peripheral nervous system disorders, ranging from microcephaly to hearing loss. These …