Innate immunity represents the semi-specific first line of defense and provides the initial host
response to tissue injury, trauma, and pathogens. Innate immunity activates the adaptive …

Due to direct contact with aquatic environment, mucosal surfaces of teleost fish are
continuously exposed to a vast number of pathogens and also inhabited by high densities of …

Rheumatoid arthritis (RA), an autoimmune disease that affects∼ 1% of the human
population, is driven by autoantibodies that target modified self-epitopes, whereas∼ 11% of …

Patients with rheumatoid arthritis can be divided into two major subsets characterized by the
presence versus absence of antibodies to citrullinated protein antigens (ACPAs) and of …

Rheumatoid arthritis (RA) is a chronic autoimmune disease considered as a multistep
process spanning from the interaction of genetic (eg, shared epitope or non-HLA loci) …

The human oral microbiome refers to an ecological community of symbiotic and pathogenic
microorganisms found in the oral cavity. The oral cavity is an environment that provides …

Objective To examine the degree to which shared risk factors explain the relationship of
periodontitis (PD) to rheumatoid arthritis (RA) and to determine the associations of PD and …

Objective To investigate protein citrullination by the periodontal pathogen Porphyromonas
gingivalis as a potential mechanism for breaking tolerance to citrullinated proteins in …

Objective To profile the abundance and diversity of subgingival oral microbiota in patients
with never‐treated, new‐onset rheumatoid arthritis (RA). Methods Periodontal disease (PD) …

Observations from numerous clinical, epidemiological and serological studies link
periodontitis with severity and progression of rheumatoid arthritis. The strong association is …