A network-biology perspective of microRNA function and dysfunction in cancer
MicroRNAs (miRNAs) participate in most aspects of cellular differentiation and homeostasis,
and consequently have roles in many pathologies, including cancer. These small non …
and consequently have roles in many pathologies, including cancer. These small non …
[HTML][HTML] Epithelial-mesenchymal transition transcription factors and miRNAs:“Plastic surgeons” of breast cancer
C Moyret-Lalle, E Ruiz, A Puisieux - World journal of clinical …, 2014 - ncbi.nlm.nih.gov
Growing evidence suggests that breast cancer cell plasticity arises due to a partial
reactivation of epithelial-mesenchymal transition (EMT) programs in order to give cells …
reactivation of epithelial-mesenchymal transition (EMT) programs in order to give cells …
Identification of microRNA-regulated gene networks by expression analysis of target genes
MicroRNAs (miRNAs) and transcription factors control eukaryotic cell proliferation,
differentiation, and metabolism through their specific gene regulatory networks. However …
differentiation, and metabolism through their specific gene regulatory networks. However …
[HTML][HTML] The EMT activator ZEB1 accelerates endosomal trafficking to establish a polarity axis in lung adenocarcinoma cells
Epithelial-to-mesenchymal transition (EMT) is a transcriptionally governed process by which
cancer cells establish a front-rear polarity axis that facilitates motility and invasion. Dynamic …
cancer cells establish a front-rear polarity axis that facilitates motility and invasion. Dynamic …
[HTML][HTML] Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells
O Yogev, D Lagos, T Enver, C Boshoff - PLoS pathogens, 2014 - journals.plos.org
Altered cell metabolism is inherently connected with pathological conditions including
cancer and viral infections. Kaposi's sarcoma-associated herpesvirus (KSHV) is the …
cancer and viral infections. Kaposi's sarcoma-associated herpesvirus (KSHV) is the …
[HTML][HTML] Regulation of B-cell development and tolerance by different members of the miR-17∼ 92 family microRNAs
M Lai, A Gonzalez-Martin, AB Cooper, H Oda… - Nature …, 2016 - nature.com
The molecular mechanisms that regulate B-cell development and tolerance remain
incompletely understood. In this study, we identify a critical role for the miR-17∼ 92 …
incompletely understood. In this study, we identify a critical role for the miR-17∼ 92 …
Epstein‐Barr virus nuclear antigen 1 (EBNA1) protein induction of epithelial‐mesenchymal transition in nasopharyngeal carcinoma cells
L Wang, WD Tian, X Xu, B Nie, J Lu, X Liu, B Zhang… - Cancer, 2014 - Wiley Online Library
BACKGROUND The Epstein‐Barr virus (EBV)‐encoded EB nuclear antigen 1 (EBNA1)
protein is required for maintenance and transmission of the viral episome in EBV‐infected …
protein is required for maintenance and transmission of the viral episome in EBV‐infected …
[HTML][HTML] Large-scale microRNA expression profiling identifies putative retinal miRNA-mRNA signaling pathways underlying form-deprivation myopia in mice
AV Tkatchenko, X Luo, TV Tkatchenko, C Vaz… - PloS one, 2016 - journals.plos.org
Development of myopia is associated with large-scale changes in ocular tissue gene
expression. Although differential expression of coding genes underlying development of …
expression. Although differential expression of coding genes underlying development of …
Regulation of miRNA processing and miRNA mediated gene repression in cancer
S Bajan, G Hutvagner - Microrna, 2014 - ingentaconnect.com
The majority of human protein-coding genes are predicted to be targets of miRNA-mediated
posttranscriptional regulation. The widespread influence of miRNAs is illustrated by their …
posttranscriptional regulation. The widespread influence of miRNAs is illustrated by their …
[HTML][HTML] Integration of miRNA and protein profiling reveals coordinated neuroadaptations in the alcohol-dependent mouse brain
The molecular mechanisms underlying alcohol dependence involve different neurochemical
systems and are brain region-dependent. Chronic Intermittent Ethanol (CIE) procedure …
systems and are brain region-dependent. Chronic Intermittent Ethanol (CIE) procedure …