Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma

CL Jones, A Degasperi, V Grandi, TD Amarante… - Scientific reports, 2021 - nature.com
T-cell non-Hodgkin's lymphomas develop following transformation of tissue resident T-cells.
We performed a meta-analysis of whole exome sequencing data from 403 patients with …

Novel targeted therapies of T cell lymphomas

K Iżykowska, K Rassek, D Korsak… - Journal of Hematology & …, 2020 - Springer
T cell lymphomas (TCL) comprise a heterogeneous group of non-Hodgkin lymphomas
(NHL) that often present at an advanced stage at the time of diagnosis and that most …

[HTML][HTML] Anaplastic large cell lymphoma: molecular pathogenesis and treatment

XR Zhang, PN Chien, SY Nam, CY Heo - Cancers, 2022 - mdpi.com
Simple Summary Anaplastic large cell lymphoma is a rare type of disease that occurs
throughout the world and has four subtypes. A summary and comparison of these subtypes …

Genetics of breast implant-associated anaplastic large cell lymphoma (BIA-ALCL)

N Oishi, RN Miranda, AL Feldman - Aesthetic surgery journal, 2019 - academic.oup.com
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL), a newly included
provisional entity in the 2016 revision of the World Health Organization classification, is a …

ALK-negative anaplastic large cell lymphoma: current concepts and molecular pathogenesis of a heterogeneous group of large T-cell lymphomas

S Pina-Oviedo, C Ortiz-Hidalgo, AA Carballo-Zarate… - Cancers, 2021 - mdpi.com
Simple Summary ALK-anaplastic large cell lymphoma (ALK-ALCL) is a rare subtype of
CD30+ large T-cell lymphoma that typically affects older adults and has a poor prognosis …

Exceptional response to the ALK and ROS1 inhibitor lorlatinib and subsequent mechanism of resistance in relapsed ALK F1174L-mutated neuroblastoma

T Liu, MD Merguerian, SP Rowe… - Molecular …, 2021 - molecularcasestudies.cshlp.org
Treatment of high-risk neuroblastoma typically incorporates multiagent chemotherapy,
surgery, radiation therapy, autologous stem cell transplantation, immunotherapy, and …

How I diagnose anaplastic large cell lymphoma

C Amador, AL Feldman - American journal of clinical pathology, 2021 - academic.oup.com
Objectives This review describes our approach to the diagnosis of all 4 anaplastic large cell
lymphoma (ALCL) entities. Methods ALCLs are a group of CD30-positive mature T-cell …

Discovery stories of RET fusions in lung cancer: a mini-review

K Takeuchi - Frontiers in Physiology, 2019 - frontiersin.org
In 2004, a chemical inhibitor of the kinase activity of EGFR was reported to be effective in a
subset of lung cancer patients with activating somatic mutations of EGFR. It remained …

Brentuximab vedotin in Hodgkin lymphoma and anaplastic large-cell lymphoma: an evidence-based review

EM Donato, M Fernández-Zarzoso… - OncoTargets and …, 2018 - Taylor & Francis
Hodgkin lymphoma (HL) and anaplastic large-cell lymphoma (ALCL) account for~ 10% and
2%–3% of all cases of lymphoid neoplasms, respectively. Up to 30% of patients with HL are …

Brentuximab vedotin in the treatment of peripheral T cell lymphoma and cutaneous T cell lymphoma

L Shea, N Mehta-Shah - Current Hematologic Malignancy Reports, 2020 - Springer
Abstract Purpose of Review The recent development of brentuximab vedotin (BV), an
antibody-drug conjugate targeting CD30-positive cells, has led to therapeutic advances in …