Lessons to be learnt from real-world studies on immune-related adverse events with checkpoint inhibitors: a clinical perspective from pharmacovigilance
E Raschi, M Gatti, F Gelsomino, A Ardizzoni… - Targeted Oncology, 2020 - Springer
The advent of immune checkpoint inhibitors (ICIs) caused a paradigm shift both in drug
development and clinical practice; however, by virtue of their mechanism of action, the …
development and clinical practice; however, by virtue of their mechanism of action, the …
Immune-mediated hepatitis induced by immune checkpoint inhibitors: Current updates and future perspectives
Z Liu, Y Zhu, H Xie, Z Zou - Frontiers in Pharmacology, 2023 - frontiersin.org
In recent years, cancer immunotherapy has made remarkable achievements. Immune
checkpoint inhibitors (ICIs) have been used successfully in several types of cancer in the …
checkpoint inhibitors (ICIs) have been used successfully in several types of cancer in the …
Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantation
K Esfahani, TA Al-Aubodah, P Thebault… - Nature …, 2019 - nature.com
Immune checkpoint inhibitor (ICI) use remains a challenge in patients with solid organ
allografts as most would undergo rejection. In a melanoma patient in whom programmed …
allografts as most would undergo rejection. In a melanoma patient in whom programmed …
Thyroid-related adverse events induced by immune checkpoint inhibitors
Immune checkpoint inhibitors, namely anti-CTLA-4, anti-PD-1 and anti-PD-L1 monoclonal
antibodies, have emerged in the last decade as a novel form of cancer treatment, promoting …
antibodies, have emerged in the last decade as a novel form of cancer treatment, promoting …
Thyroid toxicity following immune checkpoint inhibitor treatment in advanced cancer
Background: Inhibitory antibodies against cytotoxic T lymphocyte antigen-4 (CTLA-4) and
programmed cell death-1 (PD-1) have antitumor efficacy and are now standard of care in the …
programmed cell death-1 (PD-1) have antitumor efficacy and are now standard of care in the …
Implication of the gut microbiome and microbial-derived metabolites in immune-related adverse events: emergence of novel biomarkers for cancer immunotherapy
Immune checkpoint inhibitors (ICIs) have changed how we think about tumor management.
Combinations of anti-programmed death ligand-1 (PD-L1) immunotherapy have become the …
Combinations of anti-programmed death ligand-1 (PD-L1) immunotherapy have become the …
Multidisciplinary management of locally advanced and metastatic cutaneous squamous cell carcinoma
J Claveau, J Archambault, DS Ernst… - Current …, 2020 - mdpi.com
Multidisciplinary management of locally advanced and metastatic cutaneous squamous cell
carcinoma Page 1 e399 Current Oncology, Vol. 27, No. 4, August 2020 © 2020 Multimed Inc …
carcinoma Page 1 e399 Current Oncology, Vol. 27, No. 4, August 2020 © 2020 Multimed Inc …
The gut microbiome from a biomarker to a novel therapeutic strategy for immunotherapy response in patients with lung cancer
The gastrointestinal microbiome has been shown to play a key role in determining the
responses to cancer immunotherapy, including immune checkpoint inhibitor (ICI) therapy …
responses to cancer immunotherapy, including immune checkpoint inhibitor (ICI) therapy …
[HTML][HTML] Immune checkpoint inhibitors in bone metastasis: Clinical challenges, toxicities, and mechanisms
GJ Joseph, DB Johnson, RW Johnson - Journal of Bone Oncology, 2023 - Elsevier
Immune checkpoint inhibitors (ICIs) have revolutionized the field of anti-cancer therapy over
the last decade; they provide durable clinical responses against tumors by inhibiting …
the last decade; they provide durable clinical responses against tumors by inhibiting …
Biological bases of immune-related adverse events and potential crosslinks with immunogenic effects of radiation
L Bardoscia, N Pasinetti, L Triggiani, S Cozzi… - Frontiers in …, 2021 - frontiersin.org
Immune checkpoint inhibitors have gained an established role in the treatment of different
tumors. Indeed, their use has dramatically changed the landscape of cancer care, especially …
tumors. Indeed, their use has dramatically changed the landscape of cancer care, especially …