Cannabis and synaptic reprogramming of the developing brain

A Bara, JMN Ferland, G Rompala, H Szutorisz… - Nature Reviews …, 2021 - nature.com
Recent years have been transformational in regard to the perception of the health risks and
benefits of cannabis with increased acceptance of use. This has unintended …

[HTML][HTML] The role of the endocannabinoid system and genetic variation in adolescent brain development

HC Meyer, FS Lee, DG Gee - Neuropsychopharmacology, 2018 - nature.com
During adolescence, both rodent and human studies have revealed dynamic changes in the
developmental trajectories of corticolimbic structures, which are known to contribute to the …

[PDF][PDF] Adolescence as a unique developmental period

N Jaworska, G MacQueen - Journal of psychiatry & neuroscience: JPN, 2015 - jpn.ca
Gaps exist between our understanding of adolescent brain development and clinical
research involving the treatment of adolescents with emerging or established psychiatric …

Consequences of adolescent use of alcohol and other drugs: Studies using rodent models

LP Spear - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Studies using animal models of adolescent exposure to alcohol, nicotine, cannabinoids, and
the stimulants cocaine, 3, 4-methylenedioxymethampethamine and methamphetamine have …

Annual Research Review: On the developmental neuropsychology of substance use disorders

P J. Conrod, K Nikolaou - Journal of Child Psychology and …, 2016 - Wiley Online Library
Background Adolescence represents a period of development during which critical
biological, as well as social and cognitive, changes occur that are necessary for the …

Use of marijuana: effect on brain health: a scientific statement from the American Heart Association

FD Testai, PB Gorelick, HJ Aparicio, FM Filbey… - Stroke, 2022 - Am Heart Assoc
Marijuana is perceived as a harmless drug, and its recreational use has gained popularity
among young individuals. The concentration of active ingredients in recreational …

[HTML][HTML] Sex-dependent effects of in utero cannabinoid exposure on cortical function

A Bara, A Manduca, A Bernabeu, M Borsoi, M Serviado… - Elife, 2018 - elifesciences.org
Cannabinoids can cross the placenta, thus may interfere with fetal endocannabinoid
signaling during neurodevelopment, causing long-lasting deficits. Despite increasing reports …

Polyunsaturated fatty acids and endocannabinoids in health and disease

HR Freitas, AR Isaac, R Malcher-Lopes… - Nutritional …, 2018 - Taylor & Francis
Polyunsaturated fatty acids (PUFAs) are lipid derivatives of omega-3 (docosahexaenoic
acid, DHA, and eicosapentaenoic acid, EPA) or of omega-6 (arachidonic acid, ARA) …

Crosstalk between the transcriptional regulation of dopamine D2 and cannabinoid CB1 receptors in schizophrenia: Analyses in patients and in perinatal Δ9 …

M Di Bartolomeo, T Stark, OM Maurel, FA Iannotti… - Pharmacological …, 2021 - Elsevier
Perinatal exposure to Δ 9-tetrahydrocannabinol (THC) affects brain development and might
increase the incidence of psychopathology later in life, which seems to be related to a …

Consequences of perinatal cannabis exposure

AF Scheyer, M Melis, V Trezza, OJJ Manzoni - Trends in neurosciences, 2019 - cell.com
Cannabis exposure during the perinatal period results in varied and significant
consequences in affected offspring. The prevalence of detrimental outcomes of perinatal …