Prognostic role of lactate dehydrogenase in solid tumors: a systematic review and meta-analysis of 76 studies
F Petrelli, M Cabiddu, A Coinu, K Borgonovo… - Acta …, 2015 - Taylor & Francis
Background. In cancer cells, metabolism is shifted to aerobic glycolysis with lactate
production coupled with a higher uptake of glucose as the main energy source. Lactate …
production coupled with a higher uptake of glucose as the main energy source. Lactate …
Evolution of androgen receptor targeted therapy for advanced prostate cancer
The discovery of androgen dependence in prostate cancer in 1941 by Huggins and
colleagues has remained the backbone for the treatment of this disease. However, although …
colleagues has remained the backbone for the treatment of this disease. However, although …
Circulating tumor cell biomarker panel as an individual-level surrogate for survival in metastatic castration-resistant prostate cancer
Purpose Trials in castration-resistant prostate cancer (CRPC) need new clinical end points
that are valid surrogates for survival. We evaluated circulating tumor cell (CTC) enumeration …
that are valid surrogates for survival. We evaluated circulating tumor cell (CTC) enumeration …
Impact of the site of metastases on survival in patients with metastatic prostate cancer
G Gandaglia, PI Karakiewicz, A Briganti, NM Passoni… - European urology, 2015 - Elsevier
Background Limited data exist on the impact of the site of metastases on survival in patients
with stage IV prostate cancer (PCa). Objective To investigate the role of metastatic …
with stage IV prostate cancer (PCa). Objective To investigate the role of metastatic …
Visceral disease in castration-resistant prostate cancer
CJ Pezaro, A Omlin, D Lorente, DN Rodrigues… - European urology, 2014 - Elsevier
Metastatic involvement of the viscera in men with advanced castration-resistant prostate
cancer (CRPC) has been poorly characterised to date. In 359 CRPC patients treated …
cancer (CRPC) has been poorly characterised to date. In 359 CRPC patients treated …
[HTML][HTML] Recent trends in the management of advanced prostate cancer
C Ritch, M Cookson - F1000Research, 2018 - ncbi.nlm.nih.gov
Advanced prostate cancer includes a wide spectrum of disease ranging from hormone naïve
or hormone sensitive to castration resistant, both containing populations of men who have …
or hormone sensitive to castration resistant, both containing populations of men who have …
Predicting time from metastasis to overall survival in castration-resistant prostate cancer: results from SEARCH
DM Moreira, LE Howard, KN Sourbeer… - Clinical genitourinary …, 2017 - Elsevier
Objective To identify the predictors of time from initial diagnosis of metastatic castration-
resistance prostate cancer (mCRPC) to all-cause death within the Shared Equal Access …
resistance prostate cancer (mCRPC) to all-cause death within the Shared Equal Access …
AR-V7 transcripts in whole blood RNA of patients with metastatic castration resistant prostate cancer correlate with response to abiraterone acetate
Purpose: The expression of AR-V7 (androgen receptor splice variant) 7 in circulating tumor
cells has been associated with resistance to abiraterone and enzalutamide in patients with …
cells has been associated with resistance to abiraterone and enzalutamide in patients with …
Immune response drives outcomes in prostate cancer: Implications for immunotherapy
The heterogeneity of the immune microenvironment leads to different responses in immune
checkpoint blockade therapy. We aimed to propose a robust molecular classification system …
checkpoint blockade therapy. We aimed to propose a robust molecular classification system …
miRNAs and androgen deprivation therapy for prostate cancer
MY Konoshenko, OE Bryzgunova… - Biochimica et Biophysica …, 2021 - Elsevier
Androgen deprivation therapy (ADT) is mainly used for the treatment of advanced, metastatic
or recurrent prostate cancer (PCa). However, patients progress to ADT resistance and …
or recurrent prostate cancer (PCa). However, patients progress to ADT resistance and …