Due to their high target specificity and binding affinity, therapeutic antibodies are currently
the largest class of biotherapeutics. The traditional largely empirical antibody development …

Monoclonal antibodies (mAbs) as biological macromolecules have been remarked the large
and growing pipline of the pharmaceutical market and also the most promising tool in …

Antibodies play a crucial role in the defense mechanism countering pathogens or foreign
antigens in eukaryotes. Its potential as an analytical and diagnostic tool has been exploited …

Antibodies have become an important class of therapeutic agents to treat human diseases.
To accelerate therapeutic antibody discovery, computational methods, especially machine …

Percutaneous coronary intervention (PCI) is a common procedure for the management of
coronary artery obstruction. However, it usually causes vascular wall injury leading to …

Highlights•This review paper underscores how recent advances in artificial intelligence,
particularly deep learning models, have revolutionized antibody design by accurately …

Introduction The pharmaceutical industry continues to expand its search for innovative
biotherapeutics. The comprehensive characterization of such therapeutics requires many …

Abstract The S239D/I332E mutation in both chain A and chain B of Fc is widely employed to
enhance the binding affinity of Fc to its receptor (FcγRIIIa). Despite its popularity in Fc …

Antibodies are crucial proteins produced by the immune system to eliminate harmful foreign
substances and have become pivotal therapeutic agents for treating human diseases. To …

Although antibodies, a key element of biorecognition, are frequently used as biosensor
probes, the use of these large molecules can lead to adverse effects. Fab fragments can be …