Establishments and evaluations of post‐operative adhesion animal models

Y Wang, W Zhai, L Yang, S Cheng… - Advanced …, 2023 - Wiley Online Library
After abdominopelvic surgery, there are 90–93% of patients who develop postoperative
adhesions. Post‐operative adhesions can occur after various surgical procedures, which not …

[HTML][HTML] Macrophages: From simple phagocyte to an integrative regulatory cell for inflammation and tissue regeneration—A review of the literature

A Mamilos, L Winter, VH Schmitt, F Barsch… - Cells, 2023 - mdpi.com
The understanding of macrophages and their pathophysiological role has dramatically
changed within the last decades. Macrophages represent a very interesting cell type with …

[HTML][HTML] β-glucan-coupled superparamagnetic iron oxide nanoparticles induce trained immunity to protect mice against sepsis

Y Pan, J Li, X Xia, J Wang, Q Jiang, J Yang, H Dou… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Innate immune memory, also termed “trained immunity”, is thought to protect
against experimental models of infection, including sepsis. Trained immunity via …

Mouse tissue‐resident peritoneal macrophages in homeostasis, repair, infection, and tumor metastasis

C Ardavín, N Alvarez‐Ladrón, M Ferriz… - Advanced …, 2023 - Wiley Online Library
Large peritoneal macrophages (LPMs) are long‐lived, tissue‐resident macrophages, formed
during embryonic life, developmentally and functionally confined to the peritoneal cavity …

[HTML][HTML] Chitosan-crosslinked polyvinyl alcohol anti-swelling hydrogel designed to prevent abdominal wall adhesion

Y Huang, J Zheng, G Zeng, H Xu, Y Lv, X Liang, L Jin… - Materials Today Bio, 2024 - Elsevier
Abdominal adhesion is a frequent clinical issue with a high incidence rate and
consequences following intra-abdominal surgery. Although many anti-adhesion materials …

[HTML][HTML] AICAR attenuates postoperative abdominal adhesion formation by inhibiting oxidative stress and promoting mesothelial cell repair

Y Wu, X Duan, Z Gao, N Yang, F Xue - PLoS One, 2022 - journals.plos.org
Background Postoperative abdominal adhesion is one of most common complications after
abdominal operations. 5-aminoimidazole-4-carboxyamide ribonucleoside (AICAR) is an …

[HTML][HTML] A novel barrier membrane with long-term ROS scavenging function for complete prevention of postoperative adhesion

P Gong, L Ren, X Gao, J Long, W Tian, M He - Materials & Design, 2024 - Elsevier
Local oxidative stress induced by surgical trauma has been recognized as one of
pathogenesis for postsurgical adhesion tissue formation. Herein, tannic acid (TA) based …

Cell origin and niche availability dictate the capacity of peritoneal macrophages to colonize the cavity and omentum

PA Louwe, SJ Forbes, C Bénézech, C Pridans… - …, 2022 - Wiley Online Library
The relationship between macrophages of the peritoneal cavity and the adjacent omentum
remains poorly understood. Here, we describe two populations of omental macrophages …

An anti-inflammatory chondroitin sulfate-poly (lactic-co-glycolic acid) composite electrospinning membrane for postoperative abdominal adhesion prevention

R Gao, F Li, Y Zhang, P Kong, Y Gao, J Wang… - Biomaterials …, 2023 - pubs.rsc.org
Postoperative abdominal adhesion is a very common and serious complication, resulting in
pain, intestinal obstruction and heavy economic burden. Post-injury inflammation that could …

Farnesol remodels the peritoneal cavity immune environment influencing Candida albicans pathogenesis during intra-abdominal infection

JC Hargarten, MJ Vaughan, AT Lampe… - Infection and …, 2023 - Am Soc Microbiol
Candida albi c ans is a lifelong member of the mycobiome causing mucosal candidiasis and
life-threatening, systemic, and intra-abdominal disease in immunocompromised and …