Selective three-component reductive alkylalkenylation of unbiased alkenes via carbonyl-directed nickel catalysis

F Wang, S Pan, S Zhu, L Chu - ACS Catalysis, 2022 - ACS Publications
A Ni-catalyzed enantioselective reductive three-component alkylalkenylation of β, γ-alkenyl
ketones with cis-alkenyl iodides and fluoroalkyl iodides in the presence of Mn is reported. By …

Electroreduction Enables Regioselective 1, 2‐Diarylation of Alkenes with Two Electrophiles

W Yu, S Wang, M He, Z Jiang, Y Yu, J Lan… - Angewandte …, 2023 - Wiley Online Library
Precisely introducing two similar functional groups into bulk chemical alkenes represents a
formidable route to complex molecules. Especially, the selective activation of two …

Directed Asymmetric Nickel‐Catalyzed Reductive 1, 2‐Diarylation of Electronically Unactivated Alkenes

Z Dong, Q Tang, C Xu, L Chen, H Ji… - Angewandte Chemie …, 2023 - Wiley Online Library
Abstract Transition‐metal catalyzed intermolecular 1, 2‐diarylation of electronically
unactivated alkenes has emerged as an extensive research topic in organic synthesis …

Collaboration as a Key to Advance Capabilities for Earth-Abundant Metal Catalysis

PJ Chirik, KM Engle, EM Simmons… - … Process Research & …, 2023 - ACS Publications
Earth-abundant metal (EAM) catalysis can have profound impact in the pharmaceutical
industry in terms of sustainability and cost improvements from replacing precious metals like …

Three-component asymmetric Ni-catalyzed 1, 2-dicarbofunctionalization of unactivated alkenes via stereoselective migratory insertion

O Apolinar, T Kang, TM Alturaifi… - Journal of the …, 2022 - ACS Publications
An asymmetric 1, 2-dicarbofunctionalization of unactivated alkenes with aryl iodides and
aryl/alkenylboronic esters under nickel/bioxazoline catalysis is disclosed. A wide array of …

Nickel‐Catalyzed Regioselective Intermolecular Dialkylation of Alkenylarenes: Generation of Two Vicinal C(sp3)−C(sp3) Bonds Across Alkenes**

DM Lux, V Aryal, D Niroula, R Giri - Angewandte Chemie, 2023 - Wiley Online Library
We disclose a Ni‐catalyzed regioselective dialkylation reaction of alkenylarenes with α‐
halocarbonyls and alkylzinc reagents. The reaction produces γ‐arylated alkanecarbonyl …

Enantioselective Ni‐Catalyzed Three‐Component Dicarbofunctionalization of Alkenes

Z Dong, L Song, LA Chen - ChemCatChem, 2023 - Wiley Online Library
Asymmetric multicomponent reactions are considered as efficient protocols for constructing
complex chiral molecules because of their step‐and atom‐economy. Nickel‐catalyzed …

Ni-catalyzed regio-and stereoselective alkylarylation of unactivated alkenes in γ, δ-alkenylketimines

V Aryal, LJ Chesley, D Niroula, RR Sapkota… - ACS …, 2022 - ACS Publications
We disclose a Ni-catalyzed vicinal alkylarylation of unactivated alkenes in γ, δ-
alkenylketimines with aryl halides and alkylzinc reagents. The reaction produces γ-C (sp3) …

Structurally Diverse Bench‐Stable Nickel (0) Pre‐Catalysts: A Practical Toolkit for In Situ Ligation Protocols

VT Tran, N Kim, CZ Rubel, X Wu, T Kang… - Angewandte …, 2023 - Wiley Online Library
A flurry of recent research has centered on harnessing the power of nickel catalysis in
organic synthesis. These efforts have been bolstered by contemporaneous development of …

Recent Advances in the 1, 2‐Diarylation of Alkenes

J Jose, TV Mathew - Advanced Synthesis & Catalysis, 2023 - Wiley Online Library
Alkenes are a fascinating functional class that can be converted into various structures. A
desirable and durable synthetic method for forming two C− C bonds across an olefin is the …