Numerous observational studies have suggested that there is a correlation between the
level of serum vitamin D and MS risk and disease activity. To explore this hypothesis, a …

Multiple sclerosis (MS) is a complex neurodegenerative disease affecting the central
nervous system (CNS). The onset of MS has been typically observed in individuals aged …

Vitamin D (VitD) is a prohormone most noted for the regulation of calcium and phosphate
levels in circulation, and thus of bone metabolism. Inflammatory and immune cells not only …

Over the last three decades, it has become clear that the role of vitamin D goes beyond the
regulation of calcium homeostasis and bone health. An important extraskeletal effect of …

The classical function of Vitamin D, which involves mineral balance and skeletal
maintenance, has been known for many years. With the discovery of vitamin D receptors in …

The most recent findings linking exposure to sun and vitamin D insufficiency to multiple
sclerosis (MS) are reviewed. Due to insufficient sunshine and changing lifestyles …

The immune system, innate and adaptive, is a highly evolved and complex network,
essential for promoting survival in an environment full of potential pathogens, while …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative
disease of the central nervous system (CNS). In recent years, vitamin D has gained …

Objectives To study the safety and efficacy of vitamin D3 as an add on therapy to interferon β-
1b (IFNB) in patients with multiple sclerosis (MS). Methods 1 year, double blind, placebo …

Vitamin D deficiency has been associated with the risk of multiple sclerosis, disease activity
and progression. Results from in vitro experiments, animal models and analysis of human …