Advances in psoriasis physiopathology and treatments: up to date of mechanistic insights and perspectives of novel therapies based on innovative skin drug delivery …
M Sala, A Elaissari, H Fessi - Journal of Controlled Release, 2016 - Elsevier
Psoriasis is a chronic inflammatory disease affecting mainly the skin but which can be
complicated by psoriatic arthritis (PsA). This autoimmune skin disorder concerns 2–5% of …
complicated by psoriatic arthritis (PsA). This autoimmune skin disorder concerns 2–5% of …
Tackling the various classes of nano-therapeutics employed in topical therapy of psoriasis
Psoriasis is a dermatological chronic skin condition with underlying autoimmune etiology. It
deeply affects patients' quality of life. Therefore, it was an interesting target for researchers …
deeply affects patients' quality of life. Therefore, it was an interesting target for researchers …
Application of quality by design in optimization of nanoformulations: Principle, perspectives and practices
D Birla, N Khandale, B Bashir, M ShahbazAlam… - Drug Delivery and …, 2024 - Springer
Nanoparticulate drug delivery systems (NDDS) based nanoformulations have emerged as
promising drug delivery systems. Various NDDS-based formulations have been reported …
promising drug delivery systems. Various NDDS-based formulations have been reported …
Formulation, in-vitro and in-vivo pharmacokinetic evaluation of simvastatin nanostructured lipid carrier loaded transdermal drug delivery system
S Brito Raj, KB Chandrasekhar, KB Reddy - Future Journal of …, 2019 - Springer
Background A simvastatin nanostructured lipid carrier loaded transdermal patch was
developed to enhance the bioavailability and therapeutic effect. Methods Simvastatin NLC …
developed to enhance the bioavailability and therapeutic effect. Methods Simvastatin NLC …
Comparative evaluation of dithranol-loaded nanosponges fabricated by solvent evaporation technique and melt method
Background Dithranol, a standard drug for psoriasis, has lured keen attention by virtue of its
antioxidant, anti-proliferative and anti-inflammatory activities. However, its poor stability and …
antioxidant, anti-proliferative and anti-inflammatory activities. However, its poor stability and …
Hydrogel containing PEG-coated fluconazole nanoparticles with enhanced solubility and antifungal activity
Purpose The aim of this study was to prepare fluconazole (FLC) nanoparticles coated with
polyethylene glycol (PEG) in the form of FLC-PEG-NPs and optimize the size and …
polyethylene glycol (PEG) in the form of FLC-PEG-NPs and optimize the size and …
Dithranol-loaded lipid-core nanocapsules improve the photostability and reduce the in vitro irritation potential of this drug
AL Savian, D Rodrigues, J Weber, RF Ribeiro… - Materials Science and …, 2015 - Elsevier
Dithranol is a very effective drug for the topical treatment of psoriasis. However, it has some
adverse effects such as irritation and stain in the skin that make its application and patient …
adverse effects such as irritation and stain in the skin that make its application and patient …
Hyaluronic acid-coated solid lipid nanoparticles enhance antirheumatic activity and reduce toxicity of methotrexate
Y Mirchandani, VB Patravale, S Brijesh - Nanomedicine, 2022 - Taylor & Francis
Aim: Methotrexate (MTX) is used to treat rheumatoid arthritis (RA) but is associated with
severe toxicity. To minimize these side effects of MTX, the study was undertaken to explore …
severe toxicity. To minimize these side effects of MTX, the study was undertaken to explore …
Intranasal repaglinide-solid lipid nanoparticles integrated in situ gel outperform conventional oral route in hypoglycemic activity
SM Elkarray, RM Farid, MM Abd-Alhaseeb… - Journal of Drug Delivery …, 2022 - Elsevier
Repaglinide (REP) loaded solid-lipid nanoparticles (SLNs) for intranasal administration is
the subject of the current work aiming enhancement of diabetes pharmacotherapy. SLNs …
the subject of the current work aiming enhancement of diabetes pharmacotherapy. SLNs …
[PDF][PDF] Novel topical drug carriers as a tool for treatment of psoriasis: progress and advances
Psoriasis is a chronic inflammatory skin disease portrayed by erythematous,
papulosquamous lesions. It is characterized by excessive growth and aberrant …
papulosquamous lesions. It is characterized by excessive growth and aberrant …