RNase T1 is the best known representative of a large family of ribonucleolytic proteins
secreted by fungi, mostly Aspergillus and Penicillium species. Ribotoxins stand out among …

Multiconformation continuum electrostatics (MCCE) explores different conformational
degrees of freedom in Monte Carlo calculations of protein residue and ligand pKas. Explicit …

Amphitrophic proteins are soluble, globular proteins that may-under certain conditions-
interact reversibly with a plasma membrane. How this apparent duality in the properties of a …

Coiled-coil sequences in proteins commonly share a seven-amino acid repeat with nonpolar
side chains at the first (a) and fourth (d) positions. We investigate here the role of a 3-3-1 …

The fungal pathogen Hirsutella thompsonii produces an insecticidal protein named
hirsutellin A (HtA), which has been described to be toxic to several species of mites, insect …

The BbRib gene participates in the infection process of Beauveria bassiana (B. bassiana). It
also helps pathogenic fungi to escape and defeat the insect host immune defense system by …

Fungal ribotoxins are extracellular RNases that inactivate ribosomes by cleaving a single
phosphodiester bond at the universally conserved sarcin-ricin loop of the large rRNA …

Sac7d and Sso7d are homologous, hyperthermophile proteins with a high density of
charged surface residues and potential ion pairs. To determine the relative importance of …

Hirsutellin (HtA) is intermediate in size between other ribotoxins and less specific microbial
RNases, and thus offers a unique chance to determine the minimal structural requirements …

Abstract The deletion mutant Δ (7‐22) of α‐sarcin, unlike its wild‐type protein counterpart,
lacks the specific ability to degrade rRNA in intact ribosomes and exhibits an increased …