Homeostatic regulation of cardiomyocytes plays a critical role in maintaining normal
physiological activity of cardiac tissue. Severe cardiotoxicity can lead to heart disease …

Diseases are evolving as living standards continue to improve. Cancer is the main cause of
death and a major public health problem that seriously threatens human life. Colorectal …

Cancer multidrug resistance (MDR) dramatically hindered the efficiency of standard
chemotherapy. Mitochondria are highly involved in the occurrence and development of …

Cancer has become a burgeoning global healthcare concern marked by its exponential
growth and significant economic ramifications. Though advancements in the treatment …

Ursolic acid (UA), a pentacyclic triterpenoid found in various fruits and herbs, has the
potential as an anticancer agent against multiple cancer types. Nevertheless, its clinical use …

Colorectal cancer is the third leading cause of cancer-related deaths, and the five-year
survival rate of the metastatic disease is less than 15%. Treatment approaches include …

Over the past few years, there has been a gradual increase in the incidence of cancer,
affecting individuals at younger ages. With its refractory nature and substantial fatality rate …

Colorectal cancer (CRC) ranks as the third most prevalent cancer globally, contributing to
approximately 10% of all cancer cases and representing the second leading cause of …

Colorectal cancer (CRC) is one of the most frequent causes of cancer-related death
worldwide. Chemotherapeutic agents used in CRC treatment include oxaliplatin, irinotecan …

Colorectal cancer (CRC) is the most common gastrointestinal malignancy. Doxorubicin
(DOX) is a widely utilized chemotherapy drug, but its efficacy is limited due to dose …