Structure, function, and biosynthesis of nickel‐dependent enzymes

M Alfano, C Cavazza - Protein Science, 2020 - Wiley Online Library
Nickel enzymes, present in archaea, bacteria, plants, and primitive eukaryotes are divided
into redox and nonredox enzymes and play key functions in diverse metabolic processes …

Methyl (alkyl)-coenzyme M reductases: nickel F-430-containing enzymes involved in anaerobic methane formation and in anaerobic oxidation of methane or of short …

RK Thauer - Biochemistry, 2019 - ACS Publications
Methyl-coenzyme M reductase (MCR) catalyzes the methane-forming step in methanogenic
archaea. The active enzyme harbors the nickel (I) hydrocorphin coenzyme F-430 as a …

Anaerobic digestion

M Laiq Ur Rehman, A Iqbal, CC Chang… - Water Environment …, 2019 - Wiley Online Library
Worldwide waste generation has become a topic of interest since the accumulation of this
waste has prompted environmental hazards. Among which, anaerobic digestion provides …

The origin and evolution of methanogenesis and Archaea are intertwined

R Mei, M Kaneko, H Imachi, MK Nobu - PNAS nexus, 2023 - academic.oup.com
Methanogenesis has been widely accepted as an ancient metabolism, but the precise
evolutionary trajectory remains hotly debated. Disparate theories exist regarding its …

Expression of divergent methyl/alkyl coenzyme M reductases from uncultured archaea

N Shao, Y Fan, CW Chou, S Yavari… - Communications …, 2022 - nature.com
Methanogens and anaerobic methane-oxidizing archaea (ANME) are important players in
the global carbon cycle. Methyl-coenzyme M reductase (MCR) is a key enzyme in methane …

Efficient CRISPR/Cas12a-Based Genome-Editing Toolbox for Metabolic Engineering in Methanococcus maripaludis

J Bao, E de Dios Mateos, S Scheller - ACS Synthetic Biology, 2022 - ACS Publications
The rapid-growing and genetically tractable methanogen Methanococcus maripaludis is a
promising host organism for the biotechnological conversion of carbon dioxide and …

Methyl-coenzyme M reductase and its post-translational modifications

H Chen, Q Gan, C Fan - Frontiers in microbiology, 2020 - frontiersin.org
The methyl-coenzyme M reductase (MCR) is a central enzyme in anaerobic microbial
methane metabolism, which consists of methanogenesis and anaerobic oxidation of …

Highlighting the role of archaea in urban mine waste exploitation and valorisation

A Abdel Azim, R Bellini, A Vizzarro, I Bassani, CF Pirri… - Recycling, 2023 - mdpi.com
E-materials become e-waste once they have been discarded without the intent of reuse. Due
to its rich content of metals, among which many are Critical Raw Materials (CRMs), e-waste …

Structural basis of hydrogenotrophic methanogenesis

S Shima, G Huang, T Wagner… - Annual Review of …, 2020 - annualreviews.org
Most methanogenic archaea use the rudimentary hydrogenotrophic pathway—from CO2
and H2 to methane—as the terminal step of microbial biomass degradation in anoxic …

A structural view of alkyl-coenzyme M reductases, the first step of alkane anaerobic oxidation catalyzed by archaea

ON Lemaire, T Wagner - Biochemistry, 2022 - ACS Publications
Microbial anaerobic oxidation of alkanes intrigues the scientific community by way of its
impact on the global carbon cycle, and its biotechnological applications. Archaea are …