Krüppel-like factor 4 (KLF4) is an evolutionarily conserved zinc finger-containing
transcription factor that regulates diverse cellular processes such as cell growth …

The Krüppel-like factor (KLF) family of transcription factors regulates diverse biological
processes that include proliferation, differentiation, growth, development, survival, and …

Since the first prospective identification of cancer stem cells in solid cancers the cancer stem
cell hypothesis has reemerged as a research topic of increasing interest. It postulates that …

To elucidate cellular events underlying the pluripotency of human embryonic stem cells
(hESCs), we performed parallel quantitative proteomic and phosphoproteomic analyses of …

Abstract KLF4 (GKLF/EZF) encodes a transcription factor that is associated with both tumour
suppression and oncogenesis. We describe the identification of KLF4 in a functional …

Krüppel-like factors are transcriptional regulators that influence several cellular functions,
including proliferation. Recent studies have shown that one family member, KLF4, can …

While adipogenesis is known to be controlled by a complex network of transcription factors,
less is known about the transcriptional cascade that initiates this process. We report here the …

Barrier dysfunction in inflammatory bowel disease contributes to diarrhea by a leak flux
mechanism and can cause mucosal inflammation secondary to luminal antigen uptake …

Krüppel-like factors (KLFs) are evolutionarily conserved zinc finger-containing transcription
factors with diverse regulatory functions in cell growth, proliferation, differentiation, and …

Krüppel-like factor 4 (KLF4) is highly expressed in epithelial tissues such as the gut and
skin. However, the role of KLF4 in human gastric cancer development and progression is …