[HTML][HTML] Plant defense responses to biotic stress and its interplay with fluctuating dark/light conditions

Z Iqbal, MS Iqbal, A Hashem, EF Abd_Allah… - Frontiers in Plant …, 2021 - frontiersin.org
Plants are subjected to a plethora of environmental cues that cause extreme losses to crop
productivity. Due to fluctuating environmental conditions, plants encounter difficulties in …

Cullin-RING ubiquitin ligase regulatory circuits: a quarter century beyond the F-box hypothesis

JW Harper, BA Schulman - Annual review of biochemistry, 2021 - annualreviews.org
Cullin-RING ubiquitin ligases (CRLs) are dynamic modular platforms that regulate myriad
biological processes through target-specific ubiquitylation. Our knowledge of this system …

Exosome‐like nanoparticles from Mulberry bark prevent DSS‐induced colitis via the AhR/COPS8 pathway

MK Sriwastva, ZB Deng, B Wang, Y Teng, A Kumar… - EMBO …, 2022 - embopress.org
Bark protects the tree against environmental insults. Here, we analyzed whether this
defensive strategy could be utilized to broadly enhance protection against colitis. As a proof …

Targeted protein degradation as a powerful research tool in basic biology and drug target discovery

T Wu, H Yoon, Y Xiong, SE Dixon-Clarke… - Nature Structural & …, 2020 - nature.com
Controlled perturbation of protein activity is essential to study protein function in cells and
living organisms. Small molecules that hijack the cellular protein ubiquitination machinery to …

[HTML][HTML] The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

MH Glickman, A Ciechanover - Physiological reviews, 2002 - journals.physiology.org
Between the 1960s and 1980s, most life scientists focused their attention on studies of
nucleic acids and the translation of the coded information. Protein degradation was a …

Auxin: regulation, action, and interaction

AW Woodward, B Bartel - Annals of botany, 2005 - academic.oup.com
Background The phytohormone auxin is critical for plant growth and orchestrates many
developmental processes.• Scope This review considers the complex array of mechanisms …

Function and regulation of cullin–RING ubiquitin ligases

MD Petroski, RJ Deshaies - Nature reviews Molecular cell biology, 2005 - nature.com
Cullin–RING complexes comprise the largest known class of ubiquitin ligases. Owing to the
great diversity of their substrate-receptor subunits, it is possible that there are hundreds of …

Auxin in action: signalling, transport and the control of plant growth and development

WD Teale, IA Paponov, K Palme - Nature reviews Molecular cell biology, 2006 - nature.com
Hormones have been at the centre of plant physiology research for more than a century.
Research into plant hormones (phytohormones) has at times been considered as a rather …

The ubiquitin 26S proteasome proteolytic pathway

J Smalle, RD Vierstra - Annu. Rev. Plant Biol., 2004 - annualreviews.org
▪ Abstract Much of plant physiology, growth, and development is controlled by the selective
removal of short-lived regulatory proteins. One important proteolytic pathway involves the …

[HTML][HTML] HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1

R Wang, Y Zhang, M Kieffer, H Yu, S Kepinski… - Nature …, 2016 - nature.com
Recent studies have revealed that a mild increase in environmental temperature stimulates
the growth of Arabidopsis seedlings by promoting biosynthesis of the plant hormone auxin …