The sentinel within: exploiting the immune system for cancer biomarkers
KS Anderson, J LaBaer - Journal of proteome research, 2005 - ACS Publications
The release of proteins from tumors triggers an immune response in cancer patients. These
tumor antigens arise from several mechanisms including tumor-specific alterations in protein …
tumor antigens arise from several mechanisms including tumor-specific alterations in protein …
Molecular tests for colorectal cancer screening
LJW Bosch, B Carvalho, RJA Fijneman… - Clinical colorectal …, 2011 - Elsevier
Detecting and removing high-risk adenomas and early colorectal cancer (CRC) can reduce
mortality of this disease. The noninvasive fecal occult blood test (FOBT; guaiac-based or …
mortality of this disease. The noninvasive fecal occult blood test (FOBT; guaiac-based or …
Identification of let-7–regulated oncofetal genes
B Boyerinas, SM Park, N Shomron, MM Hedegaard… - Cancer research, 2008 - AACR
MicroRNAs (miRNA) are small RNA molecules of∼ 20 to 22 nucleotides that reduce
expression of proteins through mRNA degradation and/or translational silencing. Each …
expression of proteins through mRNA degradation and/or translational silencing. Each …
RHAMM is a centrosomal protein that interacts with dynein and maintains spindle pole stability
CA Maxwell, JJ Keats, M Crainie, X Sun… - Molecular biology of …, 2003 - Am Soc Cell Biol
The receptor for hyaluronan-mediated motility (RHAMM), an acidic coiled coil protein, has
previously been characterized as a cell surface receptor for hyaluronan, and a microtubule …
previously been characterized as a cell surface receptor for hyaluronan, and a microtubule …
[HTML][HTML] Molecular evidence for a critical period in mural trophoblast development in bovine blastocysts
SA Degrelle, E Campion, C Cabau, F Piumi… - Developmental …, 2005 - Elsevier
Embryonic and extra-embryonic lineages are separated at the blastocyst stage in the mouse
at the onset of implantation but well ahead of implantation in most mammals. To provide …
at the onset of implantation but well ahead of implantation in most mammals. To provide …
Standard treatments induce antigen-specific immune responses in prostate cancer
NJ Nesslinger, RA Sahota, B Stone, K Johnson… - Clinical Cancer …, 2007 - AACR
Purpose: Prostate tumors express antigens that are recognized by the immune system in a
significant proportion of patients; however, little is known about the effect of standard …
significant proportion of patients; however, little is known about the effect of standard …
RHAMM is a multifunctional protein that regulates cancer progression
BJ Messam, C Tolg, JB McCarthy, AC Nelson… - International journal of …, 2021 - mdpi.com
The functional complexity of higher organisms is not easily accounted for by the size of their
genomes. Rather, complexity appears to be generated by transcriptional, translational, and …
genomes. Rather, complexity appears to be generated by transcriptional, translational, and …
RIOK1 mediates p53 degradation and radioresistance in colorectal cancer through phosphorylation of G3BP2
Y Chen, S Zhou, K Wan, L Yu, C Zhao, H Deng, Q Ou… - Oncogene, 2022 - nature.com
Abstract RIO Kinase 1 (RIOK1) is involved in various pathologies, including cancer.
However, the role of RIOK1 in radioresistance of colorectal cancer (CRC) remains largely …
However, the role of RIOK1 in radioresistance of colorectal cancer (CRC) remains largely …
[HTML][HTML] NAP1L1 promotes proliferation and chemoresistance in glioma by inducing CCND1/CDK4/CDK6 expression through its interaction with HDGF and activation …
Z Chen, Y Xie, H Luo, Y Song, T Que, R Hu… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
The prognosis of glioma is poor as its pathogenesis and mechanisms underlying cisplatin
chemoresistance remain unclear. Nucleosome assembly protein 1 like 1 (NAP1L1) is …
chemoresistance remain unclear. Nucleosome assembly protein 1 like 1 (NAP1L1) is …
Genetic deletion of receptor for hyaluronan-mediated motility (Rhamm) attenuates the formation of aggressive fibromatosis (desmoid tumor)
Aggressive fibromatosis (desmoid tumor) is a locally invasive soft tissue neoplasm
associated with mutations resulting in β-catenin-mediated transcriptional activation. This …
associated with mutations resulting in β-catenin-mediated transcriptional activation. This …