The progress in understanding and treatment of diabetic retinopathy

AW Stitt, TM Curtis, M Chen, RJ Medina… - Progress in retinal and …, 2016 - Elsevier
Diabetic retinopathy is the most frequently occurring complication of diabetes mellitus and
remains a leading cause of vision loss globally. Its aetiology and pathology have been …

Oxidative stress and microvascular alterations in diabetic retinopathy: future therapies

ML Rodríguez, S Pérez, S Mena-Mollá… - Oxidative Medicine …, 2019 - Wiley Online Library
Diabetes is a disease that can be treated with oral antidiabetic agents and/or insulin.
However, patients' metabolic control is inadequate in a high percentage of them and a major …

[HTML][HTML] The hypoglycemic potential of phenolics from functional foods and their mechanisms

O Golovinskaia, CK Wang - Food Science and Human Wellness, 2023 - Elsevier
Long-term postprandial hyperglycemia is a primary risk factor for developing chronic
metabolic diseases such as obesity, type 2 diabetes, and cardiovascular disease. Chronic …

Endothelial dysfunction in diabetic retinopathy

F Gui, Z You, S Fu, H Wu, Y Zhang - Frontiers in Endocrinology, 2020 - frontiersin.org
Diabetic retinopathy (DR) is a diabetic complication which affects retinal function and results
in severe loss of vision and relevant retinal diseases. Retinal vascular dysfunction caused …

Involvement of advanced glycation end products in the pathogenesis of diabetic retinopathy

J Xu, LJ Chen, J Yu, HJ Wang, F Zhang… - Cellular Physiology and …, 2018 - karger.com
Diabetic retinopathy (DR) is a common and devastating microvascular complication of
diabetes and a major cause of acquired blindness in young adults. Advanced glycation end …

Early detection of diabetic retinopathy

H Safi, S Safi, A Hafezi-Moghadam… - Survey of ophthalmology, 2018 - Elsevier
Diabetic retinopathy (DR) is a primary cause of visual impairment worldwide. Diabetes
mellitus may be associated with ophthalmoscopically nonvisible neurovascular damage that …

Advanced glycation end-products and diabetic neuropathy of the retina

T Oshitari - International journal of molecular sciences, 2023 - mdpi.com
Diabetic retinopathy is a tissue-specific neurovascular impairment of the retina in patients
with both type 1 and type 2 diabetes. Several pathological factors are involved in the …

Role of oxidative stress in ocular diseases: a balancing act

DY Shu, S Chaudhary, KS Cho, A Lennikov, WP Miller… - Metabolites, 2023 - mdpi.com
Redox homeostasis is a delicate balancing act of maintaining appropriate levels of
antioxidant defense mechanisms and reactive oxidizing oxygen and nitrogen species. Any …

Progress on the pathological tissue microenvironment barrier-modulated nanomedicine

H Han, L Xing, BT Chen, Y Liu, TJ Zhou, Y Wang… - Advanced Drug Delivery …, 2023 - Elsevier
Imbalance in the tissue microenvironment is the main obstacle to drug delivery and
distribution in the human body. Before penetrating the pathological tissue microenvironment …

Human vitreous in proliferative diabetic retinopathy: characterization and translational implications

IM Nawaz, S Rezzola, A Cancarini, A Russo… - Progress in retinal and …, 2019 - Elsevier
Diabetic retinopathy (DR) is one of the leading causes of visual impairment in the working-
age population. DR is a progressive eye disease caused by long-term accumulation of …