Abstract Ionotropic Receptors (IRs) are a recently characterized family of olfactory receptors
in the fruit fly, Drosophila melanogaster. IRs are not related to insect Odorant Receptors …

In the olfactory system of Drosophila melanogaster, it is relatively straightforward to target in
vivo measurements of neural activity to specific processing channels. This, together with the …

Drosophila melanogaster has a rich repertoire of innate and learned behaviors. Its 100,000-
neuron brain is a large but tractable target for comprehensive neural circuit mapping. Only …

Genetically encoded voltage indicators (GEVIs) are a promising technology for fluorescence
readout of millisecond-scale neuronal dynamics. Previous GEVIs had insufficient signaling …

We established a collection of 7,000 transgenic lines of Drosophila melanogaster.
Expression of GAL4 in each line is controlled by a different, defined fragment of genomic …

Mapping neural circuits across defined synapses is essential for understanding brain
function. Here we describe trans-Tango, a technique for anterograde transsynaptic circuit …

Nervous systems contain sensory neurons, local neurons, projection neurons, and motor
neurons. To understand how these building blocks form whole circuits, we must distil these …

The hemibrain connectome provides large-scale connectivity and morphology information
for the majority of the central brain of Drosophila melanogaster. Using this data set, we …

Background Animal behavior is governed by the activity of interconnected brain circuits.
Comprehensive brain wiring maps are thus needed in order to formulate hypotheses about …

To sense myriad environmental odors, animals have evolved multiple, large families of
divergent olfactory receptors. How and why distinct receptor repertoires and their associated …