The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine

A Meyer-Lindenberg, G Domes, P Kirsch… - Nature Reviews …, 2011 - nature.com
The neuropeptides oxytocin (OXT) and arginine vasopressin (AVP) are evolutionarily highly
conserved mediators in the regulation of complex social cognition and behaviour. Recent …

[PDF][PDF] Oxytocin receptor is not required for social attachment in prairie voles

KM Berendzen, R Sharma, MA Mandujano, Y Wei… - Neuron, 2023 - cell.com
Prairie voles are among a small group of mammals that display long-term social attachment
between mating partners. Many pharmacological studies show that signaling via the …

[HTML][HTML] Negative symptoms of schizophrenia: clinical characteristics, pathophysiological substrates, experimental models and prospects for improved treatment

MJ Millan, K Fone, T Steckler, WP Horan - European …, 2014 - Elsevier
Schizophrenia is a complex and multifactorial disorder generally diagnosed in young adults
at the time of the first psychotic episode of delusions and hallucinations. These positive …

Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents

S Miyamoto, N Miyake, LF Jarskog… - Molecular …, 2012 - nature.com
Since the introduction of chlorpromazine and throughout the development of the new-
generation antipsychotic drugs (APDs) beginning with clozapine, the D 2 receptor has been …

Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice

ID Neumann, R Maloumby, DI Beiderbeck… - …, 2013 - Elsevier
The possibility to improve socio-emotional behaviors in humans by intranasal administration
of synthetic oxytocin (OXT) attracts increasing attention, but its uptake into the brain has …

The “Reading the Mind in the Eyes” test: Systematic review of psychometric properties and a validation study in Italy

M Vellante, S Baron-Cohen, M Melis… - Cognitive …, 2013 - Taylor & Francis
Introduction. The “Reading the Mind in the Eyes” test (henceforth, Eyes test) is a simple but
advanced Theory of Mind test, and it is widely used across different cultures. This study …

Oxytocin conditions intergroup relations through upregulated in-group empathy, cooperation, conformity, and defense

CKW De Dreu, ME Kret - Biological psychiatry, 2016 - Elsevier
Humans live in, rely on, and contribute to groups. Evolution may have biologically prepared
them to quickly identify others as belonging to the in-group (vs. not), to decode emotional …

Sniffing around oxytocin: review and meta-analyses of trials in healthy and clinical groups with implications for pharmacotherapy

MJ Bakermans-Kranenburg… - Translational …, 2013 - nature.com
The popularity of oxytocin (OT) has grown exponentially during the past decade, and so has
the number of OT trials in healthy and clinical groups. We take stock of the evidence from …

Modulating social behavior with oxytocin: how does it work? What does it mean?

PS Churchland, P Winkielman - Hormones and behavior, 2012 - Elsevier
Among its many roles in body and brain, oxytocin influences social behavior. Understanding
the precise nature of this influence is crucial, both within the broader theoretical context of …