Volume electron microscopy

CJ Peddie, C Genoud, A Kreshuk, K Meechan… - Nature Reviews …, 2022 - nature.com
Life exists in three dimensions, but until the turn of the century most electron microscopy
methods provided only 2D image data. Recently, electron microscopy techniques capable of …

Recent advances in neuropeptide signaling in Drosophila, from genes to physiology and behavior

DR Nässel, M Zandawala - Progress in neurobiology, 2019 - Elsevier
This review focuses on neuropeptides and peptide hormones, the largest and most diverse
class of neuroactive substances, known in Drosophila and other animals to play roles in …

Transforming descending input into behavior: The organization of premotor circuits in the Drosophila Male Adult Nerve Cord connectome

HSJ Cheong, K Eichler, T Stürner, SK Asinof… - bioRxiv, 2023 - biorxiv.org
In most animals, a relatively small number of descending neurons (DNs) connect higher
brain centers in the animal's head to circuits and motor neurons (MNs) in the nerve cord of …

The long and the short of it–a perspective on peptidergic regulation of circuits and behaviour

G Jékely, S Melzer, I Beets… - Journal of …, 2018 - journals.biologists.com
Neuropeptides are the most diverse class of chemical modulators in nervous systems. They
contribute to extensive modulation of circuit activity and have profound influences on animal …

Whole-animal connectome and cell-type complement of the three-segmented Platynereis dumerilii larva

C Verasztó, S Jasek, M Gühmann, R Shahidi, N Ueda… - BioRxiv, 2020 - biorxiv.org
Nervous systems coordinate effectors across the body during movements. We know little
about the cellular-level structure of synaptic circuits for such body-wide control. Here we …

Synaptic and peptidergic connectome of a neurosecretory center in the annelid brain

EA Williams, C Verasztó, S Jasek, M Conzelmann… - Elife, 2017 - elifesciences.org
Neurosecretory centers in animal brains use peptidergic signaling to influence physiology
and behavior. Understanding neurosecretory center function requires mapping cell types …

The Nereid on the rise: Platynereis as a model system

BD Özpolat, N Randel, EA Williams… - EvoDevo, 2021 - Springer
Abstract The Nereid Platynereis dumerilii (Audouin and Milne Edwards (Annales des
Sciences Naturelles 1: 195–269, 1833) is a marine annelid that belongs to the Nereididae, a …

Neuropeptides and oligopeptidases in schizophrenia

B Rodríguez, JV Nani, PGC Almeida, E Brietzke… - Neuroscience & …, 2020 - Elsevier
Schizophrenia (SCZ) is a complex psychiatric disorder with severe impact on patient's
livelihood. In the last years, the importance of neuropeptides in SCZ and other CNS …

Neural circuitry of a polycystin-mediated hydrodynamic startle response for predator avoidance

LA Bezares-Calderon, J Berger, S Jasek, C Veraszto… - Elife, 2018 - elifesciences.org
Startle responses triggered by aversive stimuli including predators are widespread across
animals. These coordinated whole-body actions require the rapid and simultaneous …

Ciliomotor circuitry underlying whole-body coordination of ciliary activity in the Platynereis larva

C Verasztó, N Ueda, LA Bezares-Calderón, A Panzera… - Elife, 2017 - elifesciences.org
Ciliated surfaces harbouring synchronously beating cilia can generate fluid flow or drive
locomotion. In ciliary swimmers, ciliary beating, arrests, and changes in beat frequency are …