The mammalian unfolded protein response

M Schröder, RJ Kaufman - Annu. Rev. Biochem., 2005 - annualreviews.org
▪ Abstract In the endoplasmic reticulum (ER), secretory and transmembrane proteins fold into
their native conformation and undergo posttranslational modifications important for their …

ER stress and the unfolded protein response

M Schröder, RJ Kaufman - Mutation Research/Fundamental and Molecular …, 2005 - Elsevier
Conformational diseases are caused by mutations altering the folding pathway or final
conformation of a protein. Many conformational diseases are caused by mutations in …

Arabidopsis MAP kinase 4 negatively regulates systemic acquired resistance

M Petersen, P Brodersen, H Naested, E Andreasson… - Cell, 2000 - cell.com
Transposon inactivation of Arabidopsis MAP kinase 4 produced the mpk4 mutant exhibiting
constitutive systemic acquired resistance (SAR) including elevated salicylic acid (SA) levels …

Endoplasmic reticulum protein quality control and its relationship to environmental stress responses in plants

JX Liu, SH Howell - The Plant Cell, 2010 - academic.oup.com
The endoplasmic reticulum (ER) has a sophisticated quality control (QC) system to eliminate
improperly folded proteins from the secretory pathway. Given that protein folding is such a …

Emerging functions of the unfolded protein response in immunity

S Janssens, B Pulendran, BN Lambrecht - Nature immunology, 2014 - nature.com
The unfolded protein response (UPR) has traditionally been viewed as an adaptive
response triggered by the accumulation of unfolded proteins in the endoplasmic reticulum …

An Endoplasmic Reticulum Stress Response in Arabidopsis Is Mediated by Proteolytic Processing and Nuclear Relocation of a Membrane-Associated Transcription …

JX Liu, R Srivastava, P Che, SH Howell - The Plant Cell, 2007 - academic.oup.com
Stresses leading to the accumulation of misfolded proteins in the endoplasmic reticulum
(ER) elicit a highly conserved ER stress response in plants called the unfolded protein …

Induction of protein secretory pathway is required for systemic acquired resistance

D Wang, ND Weaver, M Kesarwani, X Dong - Science, 2005 - science.org
In plants, systemic acquired resistance (SAR) is established as a result of NPR1-regulated
expression of pathogenesis-related (PR) genes. Using gene expression profiling in …

Salt stress responses in Arabidopsis utilize a signal transduction pathway related to endoplasmic reticulum stress signaling

JX Liu, R Srivastava, P Che, SH Howell - The Plant Journal, 2007 - Wiley Online Library
We describe a signaling pathway that mediates salt stress responses in Arabidopsis. The
response is mechanistically related to endoplasmic reticulum (ER) stress responses …

Managing the protein folding demands in the endoplasmic reticulum of plants

JX Liu, SH Howell - New Phytologist, 2016 - Wiley Online Library
Endoplasmic reticulum (ER) stress occurs in plants during certain developmental stages or
under adverse environmental conditions, as a result of the accumulation of unfolded or …

Biology of callose (β-1, 3-glucan) turnover at plasmodesmata

R Zavaliev, S Ueki, BL Epel, V Citovsky - Protoplasma, 2011 - Springer
The turnover of callose (β-1, 3-glucan) within cell walls is an essential process affecting
many developmental, physiological and stress related processes in plants. The deposition …