Cells inherit two centrioles, the older of which is uniquely capable of generating a cilium.
Using proteomics and superresolved imaging, we identify a module that we term DISCO …

In eukaryotes, the dynamic assembly of microtubules (MT) plays an important role in
numerous cellular processes. The underlying mechanism of GTP triggering MT assembly is …

In this study, a series of 2-Aryl-1H-benzo [d] imidazole derivatives were developed to target
intra-and extracellular microtubule networks. Compounds O-7 and O-10 showed impressive …

Worldwide, Lung cancer is the leading cause of cancer-related death and poses a direct
health threat, non-small cell lung cancer (NSCLC) is the most common type. In this study, we …

Oral cancer is a prevalent global health issue, with significant morbidity and mortality rates.
Despite available preventive measures, it remains one of the most common cancers …

Abstract Octamer transcription factor 1 (OCT 1) is an androgen receptor (AR)‐interacting
partner and regulates the expression of target genes in prostate cancer cells. However, the …

Sheepgrass (Leymus chinensis (Trin.) Tzvel.) is an economically and ecologically important
forage in the grass family. Self-incompatibility (SI) limits its seed production due to the low …

In cells, microtubule dynamics are regulated by plus-end tracking proteins (+ TIPs). End-
binding protein 1 (EB1, also known as MAPRE1) acts as a master regulator of+ TIP networks …

The centrosome executes diverse functions including the nucleation and organization of
microtubules. A subset of centrosomal proteins is found to be involved in regulating the …

Centrosomal proteins play critical roles in ciliogenesis. Mutations in many centrosomal
proteins have been documented to contribute to developmental defects and cilium‐related …