The transforming growth factor-β (TGFβ) family factors induce pleiotropic effects and are
involved in the regulation of most normal and pathological cellular processes. The activity of …

Embryonic stem cells (ESCs) maintain high genomic plasticity, which is essential for their
capacity to enter diverse differentiation pathways. Posttranscriptional modifications of …

Just over ten years have passed since the seminal Takahashi‐Yamanaka paper, and while
most attention nowadays is on induced, embryonic, and cancer stem cells, much of the …

Embryonic development is strictly controlled by functionality of genes in which the existing
networks can act both on transcription and translation regulation. Germ cell cancers (GCC) …

The finding of a reliable and abundant source of stem cells for the replacement of missing
neurons in nervous system diseases requires extensive characterization of neural …

Gene activation of HOX clusters is an early event in embryonic development. These genes
are highly expressed and active in the vertebrate nervous system. Based on the presence of …

Abstract FGF Receptor‐1 (FGFR1), a membrane‐targeted protein, is also involved in
independent direct nuclear signaling. We show that nuclear accumulation of FGFR1 is a …

Pax6 plays an important role in embryonic cell (ES) differentiation during embryonic
development. Expression of Pax6 undergoes from a low level to high levels following ES cell …

Abstract Nuclear factor Y (NF‐Y) is a histone substitute protein that specifically binds to the
CCAAT box of the target genes and thereby promotes their regulation. NF‐Y transcription …

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a structurally endogenous
peptide with many biological roles. Maxadilan, a 61-amino acid vasodilatory peptide …