CD44 glycoproteins in colorectal cancer: expression, function, and prognostic value

VJM Wielenga, R van der Neut, GJA Offerhaus… - Advances in cancer …, 1999 - Elsevier
Publisher Summary The chapter reviews the expression, regulation, and prognostic value of
CD44 in colorectal cancer. The chapter presents a model for CD44 function in colorectal …

Pathobiology of colorectal cancer hepatic metastases with an emphasis on prognostic factors

MP LeGolvan, M Resnick - Journal of surgical oncology, 2010 - Wiley Online Library
Colorectal cancer is the second leading cause of cancer related death in the United States.
The majority of these deaths are due to metastasis, with the liver easily accounting as the …

Expression of the hyaluronan receptor, CD44S, in epithelial ovarian cancer is an independent predictor of survival

S Kayastha, AN, S Piver, J Mukkamalla… - Clinical Cancer …, 1999 - AACR
Most ovarian carcinomas present at advanced stage, principally as the result of
dissemination to peritoneal sites. Standard CD44 (CD44S) is the principal receptor for …

Identification of novel alternative splicing isoform biomarkers and their association with overall survival in colorectal cancer

H Lian, A Wang, Y Shen, Q Wang, Z Zhou, R Zhang… - BMC …, 2020 - Springer
Background Alternative splicing (AS) is an important mechanism of regulating eukaryotic
gene expression. Understanding the most common AS events in colorectal cancer (CRC) …

Immunohistochemical expression of the CD44 variant 6 in colorectal adenocarcinoma

T Ishida - Surgery today, 2000 - Springer
The CD44 variant 6 (CD44 v6) has been postulated to be involved in both carcinogenesis
and tumor progression. In the present study, CD44 v6 was stained immunohistochemically …

Molecular detection of cancer cells by competitive reverse transcription-polymerase chain reaction analysis of specific CD44 variant RNAs

I Okamoto, J Sasaki, T Morisaki, H Saya… - JNCI: Journal of the …, 1998 - academic.oup.com
Background: CD44 is a cell surface glycoprotein implicated in such diverse biologic
processes as lymphocyte activation and homing, extracellular matrix adhesion, and cellular …

Search for epithelial-specific mRNAs in peripheral blood of patients with colon cancer by RT-PCR.

R Solmi, P De Sanctis, C Zucchini… - International …, 2004 - spandidos-publications.com
Research has widely supported the efficacy of screening for colorectal cancer in reducing
mortality. A blood-based assay potentially represents a more accessible early detection tool …

CD44: A New Prognostic Marker in Colorectal Cancer?

P Ziranu, A Pretta, V Aimola, F Cau, S Mariani… - Cancers, 2024 - mdpi.com
Simple Summary CD44 is a crucial factor in colorectal cancer, with specific isoforms
demonstrating their significance in the development, progression, metastasis, and …

[HTML][HTML] Levels of v5 and v6 CD44 splice variants in serum of patients with colorectal cancer are not correlated with pT stage, histopathological grade of malignancy …

B Zalewski - World journal of gastroenterology, 2004 - ncbi.nlm.nih.gov
AIM: This study was designed to compare the levels of v5 and v6 splice variants of CD44
evaluated using ELISA test in the serum of patients with colorectal cancer in different stages …

Demonstration of a melanoma-specific CD44 alternative splicing pattern that remains qualitatively stable, but shows quantitative changes during tumour progression

L Raso-Barnett, B Banky, T Barbai, P Becsagh, J Timar… - PloS one, 2013 - journals.plos.org
The role of CD44 in the progression of human melanoma has mostly been characterised by
qualitative changes in expression of its individual variable exons. These exons however …