[HTML][HTML] Nanopore R10.4 metagenomic detection of blaCTX-M/blaDHA antimicrobial resistance genes and their genetic environments in stool

EI Campos-Madueno, C Aldeia, A Endimiani - Nature Communications, 2024 - nature.com
The increasing prevalence of gut colonization with CTX-M extended-spectrum β-lactamase-
and/or DHA plasmid-mediated AmpC-producing Escherichia coli is a concern. Here, we …

A multicenter study on accuracy and reproducibility of nanopore sequencing-based genotyping of bacterial pathogens

J Dabernig-Heinz, M Lohde, M Hölzer… - Journal of Clinical …, 2024 - journals.asm.org
Nanopore sequencing has shown the potential to democratize genomic pathogen
surveillance due to its ease of use and low entry cost. However, recent genotyping studies …

[HTML][HTML] Nanopore adaptive sampling enriches for antimicrobial resistance genes in microbial communities

DC Wrenn, DM Drown - GigaByte, 2023 - ncbi.nlm.nih.gov
Antimicrobial resistance (AMR) is a global public health threat. Environmental microbial
communities act as reservoirs for AMR, containing genes associated with resistance, their …

[HTML][HTML] Dynamic microbiome and mobile resistome are revealed in river biofilms from a multi-use watershed through long-read sequencing

M Mills, T Wittum, J Lee - Frontiers in Environmental Science, 2024 - frontiersin.org
The dissemination of antibiotic resistance (AR) through various environments and the role of
AR hotspots in public health crises are gaining increasing attention. Aquatic biofilms are …

Nanopore adaptive sampling effectively enriches bacterial plasmids

JU Ulrich, L Epping, T Pilz, B Walther, K Stingl… - Msystems, 2024 - Am Soc Microbiol
Bacterial plasmids play a major role in the spread of antibiotic resistance genes. However,
their characterization via DNA sequencing suffers from the low abundance of plasmid DNA …

Graph-based Nanopore Adaptive Sampling with GNASTy enables sensitive pneumococcal serotyping in complex samples

ST Horsfield, B Fok, Y Fu, P Turner, JA Lees… - bioRxiv, 2024 - biorxiv.org
Serotype surveillance of Streptococcus pneumoniae (the pneumococcus) is critical for
understanding the effectiveness of current vaccination strategies. However, existing …

Role and Relation of Microbiome to Address Antimicrobial Resistance

C Bhattacharya, MT Dinc, S Basu, R Chaudhuri… - … Resistance: Factors to …, 2024 - Springer
Antibiotic resistance (AMR) has become a significant worldwide health crisis, resulting in
millions of deaths and imposing substantial economic burdens. The extensive use of …

In-silico enrichment of bacterial plasmids by chromosomal depletion using nanopore adaptive sampling

JU Ulrich, L Epping, T Pilz, B Walther, K Stingl… - bioRxiv, 2022 - biorxiv.org
Bacterial plasmids play a major role in the spread of antibiotic resistance genes. However,
their characterization via DNA sequencing suffers from the small proportion of plasmid DNA …

Advanced Methods for Real-time Metagenomic Analysis of Nanopore Sequencing Data

JU Ulrich - 2023 - refubium.fu-berlin.de
Whole shotgun metagenomics sequencing allows researchers to retrieve information about
all organisms in a complex sample. This method enables microbiologists to detect …

Role and Relation of Microbiome to Address Antimicrobial Resistance

R Panja, J Qiu, A Aditya, CE Mason - Antimicrobial Resistance: Factors … - books.google.com
Role and Relation of Microbiome to Address Antimicrobial Resistance Page 191 Chapter 6
Role and Relation of Microbiome to Address Antimicrobial Resistance Check for updates …