The role of macronutrients, micronutrients and flavonoid polyphenols in the prevention and treatment of osteoporosis
M Martiniakova, M Babikova, V Mondockova, J Blahova… - Nutrients, 2022 - mdpi.com
Osteoporosis is considered an age-related disorder of the skeletal system, characterized
primarily by decreased bone mineral density (BMD), microstructural quality and an elevated …
primarily by decreased bone mineral density (BMD), microstructural quality and an elevated …
Botanicals in postmenopausal osteoporosis
W Słupski, P Jawień, B Nowak - Nutrients, 2021 - mdpi.com
Osteoporosis is a systemic bone disease characterized by reduced bone mass and the
deterioration of bone microarchitecture leading to bone fragility and an increased risk of …
deterioration of bone microarchitecture leading to bone fragility and an increased risk of …
Insights and implications of sexual dimorphism in osteoporosis
Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …
The osteoprotective effects of kaempferol: the evidence from in vivo and in vitro studies
Kaempferol is a dietary bioflavonoid ubiquitously found in various types of plant. It
possesses a wide range of medicinal properties suggesting its potential clinical utility that …
possesses a wide range of medicinal properties suggesting its potential clinical utility that …
Therapeutic anabolic and anticatabolic benefits of natural Chinese medicines for the treatment of osteoporosis
Osteoporosis is a bone disease characterized by increasing osseous fragility and fracture
due to the reduced bone mass and microstructural degradation. Primary pharmacological …
due to the reduced bone mass and microstructural degradation. Primary pharmacological …
[HTML][HTML] Kaempferol: Paving the path for advanced treatments in aging-related diseases
Aging-related diseases (ARDs) are a major global health concern, and the development of
effective therapies is urgently needed. Kaempferol, a flavonoid found in several plants, has …
effective therapies is urgently needed. Kaempferol, a flavonoid found in several plants, has …
“Bone-SASP” in skeletal aging
CL Fang, B Liu, M Wan - Calcified Tissue International, 2023 - Springer
Senescence is a complex cell state characterized by stable cell cycle arrest and a unique
secretory pattern known as the senescence-associated secretory phenotype (SASP). The …
secretory pattern known as the senescence-associated secretory phenotype (SASP). The …
Natural medicine delivery from 3D printed bone substitutes
Unmet medical needs in treating critical-size bone defects have led to the development of
numerous innovative bone tissue engineering implants. Although additive manufacturing …
numerous innovative bone tissue engineering implants. Although additive manufacturing …
Kaempferol attenuates wear particle-induced inflammatory osteolysis via JNK and p38-MAPK signaling pathways
X Yu, Q Wu, Z Ren, B Chen, D Wang, T Yuan… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Wear particle-induced inflammatory osteoclast activation
is a master contributor to periprosthetic osteolysis, which can cause pathological bone loss …
is a master contributor to periprosthetic osteolysis, which can cause pathological bone loss …
Kaempferol promotes bone formation in part via the mTOR signaling pathway
J Zhao, J Wu, B Xu, Z Yuan… - Molecular …, 2019 - spandidos-publications.com
Previous research indicates that kaempferol (Kae) promotes osteogenesis, but its underlying
mechanism of action remains unclear. The present study hypothesized that the osteogenic …
mechanism of action remains unclear. The present study hypothesized that the osteogenic …