Coordination chemistry of bacterial metal transport and sensing

Z Ma, FE Jacobsen, DP Giedroc - Chemical reviews, 2009 - ACS Publications
The transition or d-block metal ions manganese, iron, cobalt, nickel, copper, zinc and to a
more specialized degree molybdenum, tungsten, and vanadium have been shown to be …

Arsenic–selenium and mercury–selenium bonds in biology

J Gailer - Coordination Chemistry Reviews, 2007 - Elsevier
When rabbits are simultaneous injected with arsenite and selenite or mercuric chloride and
selenite, compounds with As–Se and Hg–Se bonds are formed in the bloodstream. The …

The structural basis of tail-anchored membrane protein recognition by Get3

A Mateja, A Szlachcic, ME Downing, M Dobosz… - Nature, 2009 - nature.com
Targeting of newly synthesized membrane proteins to the endoplasmic reticulum is an
essential cellular process. Most membrane proteins are recognized and targeted co …

Arsenic metabolism in prokaryotic and eukaryotic microbes

H Bhattacharjee, BP Rosen - Molecular microbiology of heavy metals, 2007 - Springer
This chapter will focus on recent progress on the mechanisms of metalloid uptake,
metabolism, and detoxification in bacteria, archaea, and eukaryotic microbes. One of the …

Arsenic trioxide targets Hsp60, triggering degradation of p53 and survivin

X Hu, H Li, TKY Ip, YF Cheung… - Chemical …, 2021 - pubs.rsc.org
The mechanisms of action of arsenic trioxide (ATO), a clinically used drug for the treatment
of acute promyelocytic leukemia (APL), have been actively studied mainly through …

ATPases as drug targets: learning from their structure

P Chène - Nature reviews Drug discovery, 2002 - nature.com
ATPases are involved in several cellular functions, and are at the origin of various human
diseases. They are therefore attractive drug targets, and various ATPase inhibitors are …

[HTML][HTML] Structure and association of ATP-binding cassette transporter nucleotide-binding domains

ID Kerr - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2002 - Elsevier
ATP-binding cassette transporters are responsible for the uptake and efflux of a multitude of
substances across both eukaryotic and prokaryotic membranes. Members of this family of …

Molecular determinants for ATP-binding in proteins: a data mining and quantum chemical analysis

L Mao, Y Wang, Y Liu, X Hu - Journal of molecular biology, 2004 - Elsevier
Adenosine 5′-triphosphate (ATP) plays an essential role in all forms of life. Molecular
recognition of ATP in proteins is a subject of great importance for understanding enzymatic …

MinD and role of the deviant Walker A motif, dimerization and membrane binding in oscillation

J Lutkenhaus, M Sundaramoorthy - Molecular microbiology, 2003 - Wiley Online Library
Summary The ATPase activity of MinD is required for it to oscillate between the ends of the
cell and spatially regulate cell division in Escherichia coli. It is a member of a functionally …

Structural insights into tail-anchored protein binding and membrane insertion by Get3

G Bozkurt, G Stjepanovic, F Vilardi… - Proceedings of the …, 2009 - National Acad Sciences
Tail-anchored (TA) membrane proteins are involved in a variety of important cellular
functions, including membrane fusion, protein translocation, and apoptosis. The ATPase …