Fatty liver disease-alcoholic and non-alcoholic: similar but different

SDH Malnick, P Alin, M Somin… - International Journal of …, 2022 - mdpi.com
In alcohol-induced liver disease (ALD) and in non-alcoholic fatty liver disease (NAFLD),
there are abnormal accumulations of fat in the liver. This phenomenon may be related to …

Molecular mechanisms of metabolic associated fatty liver disease (MAFLD): functional analysis of lipid metabolism pathways

OO Badmus, SA Hillhouse, CD Anderson… - Clinical …, 2022 - portlandpress.com
The metabolic-associated fatty liver disease (MAFLD) is a condition of fat accumulation in
the liver in combination with metabolic dysfunction in the form of overweight or obesity and …

Parthenolide ameliorates neurological deficits and neuroinflammation in mice with traumatic brain injury by suppressing STAT3/NF-κB and inflammasome activation

W Ding, C Cai, X Zhu, J Wang, Q Jiang - International …, 2022 - Elsevier
Background Traumatic brain injury (TBI) triggers a set of complex inflammation that results in
secondary injury. Parthenolide (PTN) is a sesquiterpene lactone extracted from the herb …

Intervention of neuroinflammation in the traumatic brain injury trajectory: In vivo and clinical approaches

NK Prabhakar, H Khan, AK Grewal, TG Singh - International …, 2022 - Elsevier
TBI has been one of the top causes of death and morbidity worldwide, yet despite enormous
efforts to discover neuroprotective therapeutics for this serious disease, no beneficial …

Iron activates cGAS-STING signaling and promotes hepatic inflammation

H Li, L Hu, L Wang, Y Wang, M Shao… - Journal of Agricultural …, 2022 - ACS Publications
Iron deposition and chronic inflammation are associated with chronic liver diseases, such as
alcoholic liver disease, nonalcoholic fatty liver disease, and chronic hepatitis B and C …

Dose‐response associations of metabolic score for insulin resistance index with nonalcoholic fatty liver disease among a nonobese Chinese population: retrospective …

X Cai, J Gao, J Hu, W Wen, Q Zhu, M Wang… - Disease …, 2022 - Wiley Online Library
Purpose. This study is aimed at investigating the association between the metabolic score
for insulin resistance (METS‐IR) index and nonalcoholic fatty liver disease (NAFLD) in the …

New and Old Key Players in Liver Cancer

ÁM Cuesta, N Palao, P Bragado… - International Journal of …, 2023 - mdpi.com
Liver cancer represents a major health problem worldwide with growing incidence and high
mortality, hepatocellular carcinoma (HCC) being the most frequent. Hepatocytes are likely …

Limonin alleviates non-alcoholic fatty liver disease by reducing lipid accumulation, suppressing inflammation and oxidative stress

Y Li, M Yang, H Lin, W Yan, G Deng, H Ye… - Frontiers in …, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
and continues to rise in the worldwide. Limonin is a triterpenoid compound widely found in …

Neurogenic hypothesis of positive psychology in stress-induced depression: adult hippocampal neurogenesis, neuroinflammation, and stress resilience

Z Wu, L Xiao, H Wang, G Wang - International Immunopharmacology, 2021 - Elsevier
Stress is an important risk factor for depression. Emerging evidence supports the hypothesis
that stress-mediated neuroinflammation destroys brain function and leads to anxiety-like and …

[HTML][HTML] Ameliorative effects of miR-423-5p against polarization of microglial cells of the M1 phenotype by targeting a NLRP3 inflammasome signaling pathway

J Cheng, J Hao, X Jiang, J Ji, T Wu, X Chen… - International …, 2021 - Elsevier
Spinal cord injury (SCI) causes sensation and motion dysfunction. Activation of microglial
cells (MCs) in the central nervous system (CNS) is heterogeneous. Heterogeneous types of …