Mn (ii) complex impregnated porous silica nanoparticles as Zn (ii)-responsive “Smart” MRI contrast agent for pancreas imaging

R Mallik, M Saha, V Singh, H Mohan… - Journal of Materials …, 2023 - pubs.rsc.org
Type-1 and type-2 diabetes mellitus are metabolic disorders governed by the functional
efficiency of pancreatic β-cells. The activities of the cells toward insulin production, storage …

The relationship between beta cell activation and SLC30A8/ZnT8 levels of the endocrine pancreas and maternal zinc deficiency in rats

E Goktepe, SB Baltaci, O Unal, N Unlukal… - Journal of Trace …, 2023 - Elsevier
Objectives Zinc, which is found in high concentrations in the β-cells of the pancreas, is also a
critical component for the endocrine functions of the pancreas. SLC30A8/ZnT8 is the carrier …

Zinc deficiency affects insulin secretion and alters insulin-regulated metabolic signaling in rats

A Nakamura, T Kido, Y Seki, M Suka - … of Trace Elements in Medicine and …, 2024 - Elsevier
Background The essential trace element zinc is important in stabilizing pancreatic insulin
secretion. Zinc not only influences the synthesis of insulin but also affects its activity. Insulin …

Zinc chloride enhances the antioxidant status, improving the functional and structural organic disturbances in streptozotocin-induced diabetes in rats

IC Anton, L Mititelu-Tartau, EG Popa, M Poroch… - Medicina, 2022 - mdpi.com
Background and Objectives: Diabetes mellitus (DM) is a complex disease affecting the
whole metabolic balance of the body and resulting in multiple organ complications …

[HTML][HTML] Complementary Approaches to Interrogate Mitophagy Flux in Pancreatic β-Cells

E Levi-D'Ancona, V Sidarala… - Journal of visualized …, 2023 - ncbi.nlm.nih.gov
Mitophagy is a quality control mechanism necessary to maintain optimal mitochondrial
function. Dysfunctional β-cell mitophagy results in insufficient insulin release. Advanced …

Impact of dietary zinc on stimulated zinc secretion MRI in the healthy and malignant mouse prostate

V Clavijo Jordan, AF Martins, E Dao, K Geraki… - npj Imaging, 2024 - nature.com
Previous studies have shown that the zinc-responsive MRI probe, GdL1, can distinguish
healthy versus malignant prostate tissues based upon differences in zinc content and …

Assessment of Mitophagy Flux in Pancreatic β-Cells Using Effective and Robust Complementary Approaches (Video)| JoVE

E Levi-D'Ancona, V Sidarala… - JoVE (Journal of …, 2023 - jove.com
Mitophagy is a quality control mechanism necessary to maintain optimal mitochondrial
function. Dysfunctional β-cell mitophagy results in insufficient insulin release. Advanced …

[PDF][PDF] Radiological Modalities and Diabetes: A Review

KM Kelis, AD Almutairi, TA Aldrewesh… - Journal of Clinical …, 2022 - researchgate.net
Diabetes has become a health care problem of increasing concern in the world as number
of individuals with disease are on the rise over the past 2 decades. Imaging technologies …

[引用][C] Lanthanide-based responsive MRI contrast agents

CS Bonnet, É Tóth - 2024 - Elsevier