Free radicals, antioxidant defense systems, and schizophrenia

JQ Wu, TR Kosten, XY Zhang - Progress in Neuro-Psychopharmacology …, 2013 - Elsevier
The etiopathogenic mechanisms of schizophrenia are to date unknown, although several
hypotheses have been suggested. Accumulating evidence suggests that excessive free …

Predictors of outcome in early-onset psychosis: a systematic review

CM Díaz-Caneja, L Pina-Camacho… - npj …, 2015 - nature.com
Given the global burden of psychotic disorders, the identification of patients with early-onset
psychosis (EOP; that is, onset before the age of 18) at higher risk of adverse outcome should …

A meta-analysis of oxidative stress markers in depression

T Liu, S Zhong, X Liao, J Chen, T He, S Lai, Y Jia - PloS one, 2015 - journals.plos.org
Object Studies have suggested that depression was accompanied by oxidative stress
dysregulation, including abnormal total antioxidant capacity (TAC), antioxidants, free …

Meta-analysis of oxidative stress in schizophrenia

J Flatow, P Buckley, BJ Miller - Biological psychiatry, 2013 - Elsevier
Background Schizophrenia is associated with impaired antioxidant defense, including
abnormal serum, plasma, and red blood cell (RBC) oxidative stress parameters. We …

Antioxidants as potential therapeutics for neuropsychiatric disorders

CD Pandya, KR Howell, A Pillai - Progress in Neuro-Psychopharmacology …, 2013 - Elsevier
Oxidative stress has been implicated in the pathophysiology of many neuropsychiatric
disorders such as schizophrenia, bipolar disorder, major depression etc. Both genetic and …

Major depressive disorder and oxidative stress: a review of peripheral and genetic biomarkers according to clinical characteristics and disease stages

AEK Ait Tayeb, V Poinsignon, K Chappell, J Bouligand… - Antioxidants, 2023 - mdpi.com
Major depressive disorder (MDD) is currently the main cause of disability worldwide, but its
pathophysiology remains largely unknown, especially given its high heterogeneity in terms …

Neuroinflammation and oxidative stress in psychosis and psychosis risk

H Barron, S Hafizi, AC Andreazza… - International journal of …, 2017 - mdpi.com
Although our understanding of psychotic disorders has advanced substantially in the past
few decades, very little has changed in the standard of care for these illnesses since the …

Oxidative stress parameters and antioxidants in adults with unipolar or bipolar depression versus healthy controls: Systematic review and meta-analysis

S Jiménez-Fernández, M Gurpegui… - Journal of Affective …, 2022 - Elsevier
Background To study differences in oxidative stress markers and antioxidants among
patients with bipolar depression (BPD) and unipolar depression (UPD). Methods Data …

Implications for reactive oxygen species in schizophrenia pathogenesis

M Koga, AV Serritella, A Sawa, TW Sedlak - Schizophrenia research, 2016 - Elsevier
Oxidative stress is a well-recognized participant in the pathophysiology of multiple brain
disorders, particularly neurodegenerative conditions such as Alzheimer's and Parkinson's …

Pro-/anti-inflammatory dysregulation in patients with first episode of psychosis: toward an integrative inflammatory hypothesis of schizophrenia

B García-Bueno, M Bioque, KS Mac-Dowell… - Schizophrenia …, 2014 - academic.oup.com
Background: Schizophrenia is a chronic syndrome of unknown etiology, predominantly
defined by signs of psychosis. The onset of the disorder occurs typically in late adolescence …