Monocytes and Macrophages in COVID-19
COVID-19 is a contagious viral disease caused by SARS-CoV-2 that led to an ongoing
pandemic with massive global health and socioeconomic consequences. The disease is …
pandemic with massive global health and socioeconomic consequences. The disease is …
Neutrophils in COVID-19
N Reusch, E De Domenico, L Bonaguro… - Frontiers in …, 2021 - frontiersin.org
Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that
neutrophils play an important role in the pathophysiology, particularly in those with severe …
neutrophils play an important role in the pathophysiology, particularly in those with severe …
Swarm learning for decentralized and confidential clinical machine learning
S Warnat-Herresthal, H Schultze, KL Shastry… - Nature, 2021 - nature.com
Fast and reliable detection of patients with severe and heterogeneous illnesses is a major
goal of precision medicine,. Patients with leukaemia can be identified using machine …
goal of precision medicine,. Patients with leukaemia can be identified using machine …
Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …
infectious respiratory virus which is responsible for the coronavirus disease 2019 (COVID …
Local and systemic responses to SARS-CoV-2 infection in children and adults
M Yoshida, KB Worlock, N Huang, RGH Lindeboom… - Nature, 2022 - nature.com
It is not fully understood why COVID-19 is typically milder in children,–. Here, to examine the
differences between children and adults in their response to SARS-CoV-2 infection, we …
differences between children and adults in their response to SARS-CoV-2 infection, we …
Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress
E Montaldo, E Lusito, V Bianchessi, N Caronni… - Nature …, 2022 - nature.com
Traditionally viewed as poorly plastic, neutrophils are now recognized as functionally
diverse; however, the extent and determinants of neutrophil heterogeneity in humans remain …
diverse; however, the extent and determinants of neutrophil heterogeneity in humans remain …
RNAInter v4. 0: RNA interactome repository with redefined confidence scoring system and improved accessibility
Establishing an RNA-associated interaction repository facilitates the system-level
understanding of RNA functions. However, as these interactions are distributed throughout …
understanding of RNA functions. However, as these interactions are distributed throughout …
Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19
Our understanding of protective versus pathological immune responses to SARS-CoV-2, the
virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of …
virus that causes coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of …
[HTML][HTML] COVID-19 and the human innate immune system
JL Schultze, AC Aschenbrenner - Cell, 2021 - cell.com
The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the
human population represents a tremendous medical and economic crisis. Innate immunity …
human population represents a tremendous medical and economic crisis. Innate immunity …
A guide to systems-level immunomics
The immune system is highly complex and distributed throughout an organism, with
hundreds to thousands of cell states existing in parallel with diverse molecular pathways …
hundreds to thousands of cell states existing in parallel with diverse molecular pathways …