Current challenges and future opportunities of phage therapy
Antibiotic resistance is a major public health challenge worldwide, whose implications for
global health might be devastating if novel antibacterial strategies are not quickly …
global health might be devastating if novel antibacterial strategies are not quickly …
Bacterial biofilm destruction: A focused review on the recent use of phage-based strategies with other antibiofilm agents
Biofilms are bacterial communities that live in association with biotic or abiotic surfaces and
enclosed in an extracellular polymeric substance. Their formation on both biotic and abiotic …
enclosed in an extracellular polymeric substance. Their formation on both biotic and abiotic …
Development and use of personalized bacteriophage-based therapeutic cocktails to treat a patient with a disseminated resistant Acinetobacter baumannii infection
RT Schooley, B Biswas, JJ Gill… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Widespread antibiotic use in clinical medicine and the livestock industry has contributed to
the global spread of multidrug-resistant (MDR) bacterial pathogens, including Acinetobacter …
the global spread of multidrug-resistant (MDR) bacterial pathogens, including Acinetobacter …
Phage therapy for respiratory infections
A respiratory infection caused by antibiotic-resistant bacteria can be life-threatening. In
recent years, there has been tremendous effort put towards therapeutic application of …
recent years, there has been tremendous effort put towards therapeutic application of …
[HTML][HTML] The resurgence of phage-based therapy in the era of increasing antibiotic resistance: from research progress to challenges and prospects
NJ Anyaegbunam, CC Anekpo… - Microbiological …, 2022 - Elsevier
Phage therapy was implemented almost a century ago but was subsequently abandoned
when antibiotics emerged. However, the rapid emergence of drug-resistant, which has …
when antibiotics emerged. However, the rapid emergence of drug-resistant, which has …
[HTML][HTML] Secondary bacterial infections during pulmonary viral disease: phage therapeutics as alternatives to antibiotics?
Secondary bacterial infections manifest during or after a viral infection (s) and can lead to
negative outcomes and sometimes fatal clinical complications. Research and development …
negative outcomes and sometimes fatal clinical complications. Research and development …
[HTML][HTML] Isolation and in vitro evaluation of bacteriophages against MDR-bacterial isolates from septic wound infections
Multi-drug resistance has become a major problem for the treatment of pathogenic bacterial
infections. The use of bacteriophages is an attractive approach to overcome the problem of …
infections. The use of bacteriophages is an attractive approach to overcome the problem of …
Bacteriophage PEV20 and Ciprofloxacin Combination Treatment Enhances Removal of Pseudomonas aeruginosa Biofilm Isolated from Cystic Fibrosis and Wound …
Antibiotic resistance in Pseudomonas aeruginosa biofilms necessitates the need for novel
antimicrobial therapy with anti-biofilm properties. Bacteriophages (phages) are recognized …
antimicrobial therapy with anti-biofilm properties. Bacteriophages (phages) are recognized …
Synergy of nebulized phage PEV20 and ciprofloxacin combination against Pseudomonas aeruginosa
Y Lin, RYK Chang, WJ Britton, S Morales… - International journal of …, 2018 - Elsevier
Nebulization is currently used for delivery of antibiotics for respiratory infections.
Bacteriophages (or phages) are effective predators of pathogens including Pseudomonas …
Bacteriophages (or phages) are effective predators of pathogens including Pseudomonas …
Synergistic activity of phage PEV20-ciprofloxacin combination powder formulation—A proof-of-principle study in a P. aeruginosa lung infection model
Combination treatment using bacteriophage and antibiotics is potentially an advanced
approach to combatting antimicrobial-resistant bacterial infections. We have recently …
approach to combatting antimicrobial-resistant bacterial infections. We have recently …