The pharmaceutical industry has been desperately searching for efficient drug discovery
methods. Organ-on-a-Chip, a cutting-edge technology that can emulate the physiological …

Worldwide nanotechnology development and application have fueled many scientific
advances, but technophilic expectations and technophobic demands must be …

Acute kidney injury (AKI) is a global health challenge of vast proportions, as approx. 13.3%
of people worldwide are affected annually. The pathophysiology of AKI is very complex, but …

The development of pharmaceutical analytical methods represents one of the most
significant aspects of drug development. Recent advances in microfabrication and …

The kidney consists of numerous cell types organized into the nephron, which is the basic
functional unit of the kidney. Any stimuli that induce loss of these cells can induce kidney …

Organ-on-a-chip devices have enabled major breakthroughs in biomedical research, but
they have yet to be successfully translated to the pharmaceutical industry. Traditional …

Over the past decade, traditional Chinese medicine (TCM) has widely embraced systems
biology and its various data integration approaches to promote its modernization. Thus …

Abstract Organ-on-a-chip (OOC, organ chip) technology can closely simulate the human
microenvironment, synthesize organ-like functional units on a fluidic chip substrate, and …

The function and susceptibility of various drugs are tested with renal proximal tubular
epithelial cells; yet, replicating the morphology and kidneys function using the currently …

Organ-on-a-chip academic research is in its blossom. Drug toxicity evaluation is a promising
area in which organ-on-a-chip technology can apply. A unique advantage of organ-on-a …