[HTML][HTML] Network regulation of microRNA biogenesis and target interaction

S Komatsu, H Kitai, HI Suzuki - Cells, 2023 - mdpi.com
MicroRNAs (miRNAs) are versatile, post-transcriptional regulators of gene expression.
Canonical miRNAs are generated through the two-step DROSHA-and DICER-mediated …

[HTML][HTML] MicroRNAs involved in carcinogenesis, prognosis, therapeutic resistance, and applications in human triple-negative breast cancer

L Ding, H Gu, X Xiong, H Ao, J Cao, W Lin, M Yu, J Lin… - Cells, 2019 - mdpi.com
Triple-negative breast cancer (TNBC) is the most aggressive, prevalent, and distinct subtype
of breast cancer characterized by high recurrence rates and poor clinical prognosis, devoid …

miEAA 2.0: integrating multi-species microRNA enrichment analysis and workflow management systems

F Kern, T Fehlmann, J Solomon, L Schwed… - Nucleic acids …, 2020 - academic.oup.com
Gene set enrichment analysis has become one of the most frequently used applications in
molecular biology research. Originally developed for gene sets, the same statistical …

Triple negative breast cancer in the era of miRNA

H Sabit, E Cevik, H Tombuloglu, S Abdel-Ghany… - Critical reviews in …, 2021 - Elsevier
The objective of this review is to elucidate the role of miRNAs in triple negative breast cancer
(TNBC). To achieve our goal, we searched databases such as PubMed, ScienceDirect …

The emerging role of miRNA clusters in breast cancer progression

A Kandettu, R Radhakrishnan, S Chakrabarty… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Micro RNAs (miRNAs) are small non-coding RNAs that are essential for regulation of gene
expression of the target genes. Large number of miRNAs are organized into defined units …

[HTML][HTML] miRNA-based potential biomarkers and new molecular insights in ulcerative colitis

J Zhou, J Liu, Y Gao, L Shen, S Li… - Frontiers in Pharmacology, 2021 - frontiersin.org
Ulcerative colitis (UC) is a chronic non-specific inflammatory bowel disease, which usually
manifests as abdominal pain, diarrhea and hematochezia. The disease often recurs and is …

[HTML][HTML] microRNAs orchestrate pathophysiology of breast cancer brain metastasis: advances in therapy

RK Kanchan, JA Siddiqui, S Mahapatra, SK Batra… - Molecular cancer, 2020 - Springer
Brain metastasis (BM) predominantly occurs in triple-negative (TN) and epidermal growth
factor 2 (HER2)-positive breast cancer (BC) patients, and currently, there is an unmet need …

[HTML][HTML] The anticancer effects of flavonoids through miRNAs modulations in triple-negative breast cancer

GM Adinew, E Taka, P Mendonca, SS Messeha… - Nutrients, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) incidence rate has regularly risen over the last
decades and is expected to increase in the future. Finding novel treatment options with …

[HTML][HTML] Early downregulation of hsa-miR-144-3p in serum from drug-naïve Parkinson's disease patients

E Zago, A Dal Molin, GM Dimitri, L Xumerle… - Scientific reports, 2022 - nature.com
Advanced age represents one of the major risk factors for Parkinson's Disease. Recent
biomedical studies posit a role for microRNAs, also known to be remodelled during ageing …

[HTML][HTML] Novel miRNA targets and therapies in the triple-negative breast cancer microenvironment: an emerging hope for a challenging disease

A Qattan - International journal of molecular sciences, 2020 - mdpi.com
Treatment of triple-negative breast cancer (TNBC) remains challenging because of the
heterogeneity of the disease and lack of single targetable driving mutations. TNBC does not …