Health concerns of various nanoparticles: A review of their in vitro and in vivo toxicity

M Ajdary, MA Moosavi, M Rahmati, M Falahati… - Nanomaterials, 2018 - mdpi.com
Nanoparticles (NPs) are currently used in diagnosis and treatment of many human diseases,
including autoimmune diseases and cancer. However, cytotoxic effects of NPs on normal …

Isothermal titration calorimetry as a complementary method for investigating nanoparticle–protein interactions

D Prozeller, S Morsbach, K Landfester - Nanoscale, 2019 - pubs.rsc.org
Isothermal titration calorimetry (ITC) is a complementary technique that can be used for
investigations of protein adsorption on nanomaterials, as it quantifies the thermodynamic …

Novel perspective into the interaction behavior study of the cyanidin with human serum albumin-holo transferrin complex: Spectroscopic, calorimetric and molecular …

S Khashkhashi-Moghadam, S Ezazi-Toroghi… - Journal of Molecular …, 2022 - Elsevier
We examined the inducement of an interaction between two carrier proteins, human serum
albumin (HSA) and human holo transferrin (HTF) within the presence of cyanidinin the form …

pH-Mediated mucus penetration of zwitterionic polydopamine-modified silica nanoparticles

Y Ma, Y Guo, S Liu, Y Hu, C Yang, G Cheng, C Xue… - Nano Letters, 2023 - ACS Publications
Zwitterionic polymers have emerged as promising trans-mucus nanocarriers due to their
superior antifouling properties. However, for pH-sensitive zwitterionic polymers, the effect of …

Protein-gold nanoparticle interactions and their possible impact on biomedical applications

J Liu, Q Peng - Acta biomaterialia, 2017 - Elsevier
In the past few years, concerns of protein-gold nanoparticles (AuNP) interaction have been
continuously growing in numerous potential biomedical applications. Despite the advances …

Techniques for the experimental investigation of the protein corona

C Carrillo-Carrion, M Carril, WJ Parak - Current Opinion in Biotechnology, 2017 - Elsevier
Highlights•Direct versus indirect analysis of the protein corona.•In situ measurements of
protein corona versus measurements requiring purification.•Characterization apart from …

Thermodynamics of adsorption on nanocellulose surfaces

S Lombardo, W Thielemans - Cellulose, 2019 - Springer
Understanding the thermodynamic interactions of cellulose nanomaterials with their
environment is important to understand the forces behind their self-organization and co …

Nanoparticle-protein corona complex: understanding multiple interactions between environmental factors, corona formation, and biological activity

A Tomak, S Cesmeli, BD Hanoglu, D Winkler… - …, 2021 - Taylor & Francis
The surfaces of pristine nanoparticles become rapidly coated by proteins in biological fluids,
forming the so-called protein corona. The corona modifies key physicochemical …

Zwitterionic nanocarrier surface chemistry improves siRNA tumor delivery and silencing activity relative to polyethylene glycol

MA Jackson, TA Werfel, EJ Curvino, F Yu… - ACS …, 2017 - ACS Publications
Although siRNA-based nanomedicines hold promise for cancer treatment, conventional
siRNA–polymer complex (polyplex) nanocarrier systems have poor pharmacokinetics …

Biological effects of formation of protein corona onto nanoparticles

RK Mishra, A Ahmad, A Vyawahare, P Alam… - International journal of …, 2021 - Elsevier
Administration of nanomaterials based medicinal and drug carrier systems into systemic
circulation brings about interaction of blood components eg albumin and globulin proteins …