Non-coding RNAs in disease: from mechanisms to therapeutics
Non-coding RNAs (ncRNAs) are a heterogeneous group of transcripts that, by definition, are
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
not translated into proteins. Since their discovery, ncRNAs have emerged as important …
[HTML][HTML] Clinical and translational values of spatial transcriptomics
L Zhang, D Chen, D Song, X Liu, Y Zhang… - … and Targeted Therapy, 2022 - nature.com
The combination of spatial transcriptomics (ST) and single cell RNA sequencing (scRNA-
seq) acts as a pivotal component to bridge the pathological phenomes of human tissues with …
seq) acts as a pivotal component to bridge the pathological phenomes of human tissues with …
[HTML][HTML] miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
S Zhou, J Jin, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
world. Although considerable progress has been made in the diagnosis, treatment and …
world. Although considerable progress has been made in the diagnosis, treatment and …
Distribution of miRNA expression across human tissues
We present a human miRNA tissue atlas by determining the abundance of 1997 miRNAs in
61 tissue biopsies of different organs from two individuals collected post-mortem. One …
61 tissue biopsies of different organs from two individuals collected post-mortem. One …
miRNAs orchestration of cardiovascular diseases-Particular emphasis on diagnosis, and progression
MicroRNAs (miRNAs; miRs) are small non-coding ribonucleic acids sequences vital in
regulating gene expression. They are significant in many biological and pathological …
regulating gene expression. They are significant in many biological and pathological …
RNA-based diagnostic and therapeutic strategies for cardiovascular disease
D Lu, T Thum - Nature Reviews Cardiology, 2019 - nature.com
Cardiovascular diseases are the leading cause of death globally and are associated with
increasing financial expenditure. With the availability of next-generation sequencing …
increasing financial expenditure. With the availability of next-generation sequencing …
Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives
Recent research has demonstrated that the non-coding genome plays a key role in genetic
programming and gene regulation during development as well as in health and …
programming and gene regulation during development as well as in health and …
Circulating noncoding RNAs as biomarkers of cardiovascular disease and injury
J Viereck, T Thum - Circulation research, 2017 - Am Heart Assoc
The discovery of thousands of noncoding RNAs (ncRNAs) has expanded our view on
mammalian genomes and transcriptomes, as well as their organization and regulation …
mammalian genomes and transcriptomes, as well as their organization and regulation …
MicroRNAs in heart failure: from biomarker to target for therapy
EL Vegter, P van der Meer, LJ de Windt… - European journal of …, 2016 - Wiley Online Library
MicroRNAs (miRNAs) are increasingly recognized to play important roles in cardiovascular
diseases, including heart failure. These small, non‐coding RNAs have been identified in …
diseases, including heart failure. These small, non‐coding RNAs have been identified in …
[HTML][HTML] MicroRNA and cardiovascular diseases
HA Çakmak, M Demir - Balkan medical journal, 2020 - ncbi.nlm.nih.gov
Cardiovascular diseases are one of the most common causes of death in both developing
and developed countries worldwide. Even though there have been improvements in primary …
and developed countries worldwide. Even though there have been improvements in primary …