Immunity, atherosclerosis and cardiovascular disease

J Frostegård - BMC medicine, 2013 - Springer
Atherosclerosis, the major cause of cardiovascular disease (CVD), is a chronic inflammatory
condition with immune competent cells in lesions producing mainly pro-inflammatory …

Vein graft failure: from pathophysiology to clinical outcomes

MR De Vries, KH Simons, JW Jukema… - Nature Reviews …, 2016 - nature.com
Occlusive arterial disease is a leading cause of morbidity and mortality worldwide. Aside
from balloon angioplasty, bypass graft surgery is the most commonly performed …

Systemic lupus erythematosus and cardiovascular disease

J Frostegård - Journal of Internal Medicine, 2023 - Wiley Online Library
The prognosis in systemic lupus erythematosus (SLE) has improved due to better treatment
and care, but cardiovascular disease (CVD) still remains an important clinical problem, since …

Platelets in inflammation and atherogenesis

HM Nording, P Seizer, HF Langer - Frontiers in immunology, 2015 - frontiersin.org
Platelets contribute to processes beyond thrombus formation and may play a so far
underestimated role as an immune cell in various circumstances. This review outlines …

[HTML][HTML] Annexin A5 regulates hepatic macrophage polarization via directly targeting PKM2 and ameliorates NASH

F Xu, M Guo, W Huang, L Feng, J Zhu, K Luo, J Gao… - Redox biology, 2020 - Elsevier
Nonalcoholic steatohepatitis (NASH), the progressive form of nonalcoholic fatty liver disease
(NAFLD), is becoming a common chronic liver disease with the characteristics of steatosis …

[HTML][HTML] Prevention of atrial fibrillation after open-chest surgery with extracellular vesicle therapy

S Parent, R Vaka, Y Risha, C Ngo, P Kanda, S Nattel… - JCI insight, 2023 - ncbi.nlm.nih.gov
Almost half of patients recovering from open-chest surgery experience atrial fibrillation (AF)
that results principally from inflammation in the pericardial space surrounding the heart …

Annexin A1 counteracts chemokine-induced arterial myeloid cell recruitment

M Drechsler, R de Jong, J Rossaint, JR Viola… - Circulation …, 2015 - Am Heart Assoc
Rationale: Chemokine-controlled arterial leukocyte recruitment is a crucial process in
atherosclerosis. Formyl peptide receptor 2 (FPR2) is a chemoattractant receptor that …

Inflammation in vein graft disease

MR De Vries, PHA Quax - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
Bypass surgery is one of the most frequently used strategies to revascularize tissues
downstream occlusive atherosclerotic lesions. For venous bypass surgery the great …

[HTML][HTML] Annexin A5 ameliorates traumatic brain injury-induced neuroinflammation and neuronal ferroptosis by modulating the NF-ĸB/HMGB1 and Nrf2/HO-1 …

Y Gao, H Zhang, J Wang, F Li, X Li, T Li, C Wang… - International …, 2023 - Elsevier
Traumatic brain injury often causes poor outcomes and has few established treatments.
Neuroinflammation and ferroptosis hinder therapeutic progress in this domain. Annexin A5 …

Annexin A protein family in atherosclerosis

YZ Li, YY Wang, L Huang, YY Zhao, LH Chen… - Clinica Chimica …, 2022 - Elsevier
Atherosclerosis, a silent chronic vascular pathology, is the cause of the majority of
cardiovascular ischaemic events. Atherosclerosis is characterized by a series of deleterious …