RSV prevention in all infants: which is the most preferable strategy?

S Esposito, B Abu Raya, E Baraldi, K Flanagan… - Frontiers in …, 2022 - frontiersin.org
Respiratory syncytial virus (RSV) causes a spectrum of respiratory illnesses in infants and
young children that may lead to hospitalizations and a substantial number of outpatient …

Immune response in COVID-19: what is next?

Q Li, Y Wang, Q Sun, J Knopf, M Herrmann… - Cell Death & …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) has been a global pandemic for more
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …

[HTML][HTML] Nirsevimab for prevention of RSV in healthy late-preterm and term infants

LL Hammitt, R Dagan, Y Yuan… - … England Journal of …, 2022 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract
infection and hospitalization in infants. Nirsevimab is a monoclonal antibody to the RSV …

[HTML][HTML] Prefusion F protein–based respiratory syncytial virus immunization in pregnancy

EAF Simões, KJ Center, ATN Tita… - … England Journal of …, 2022 - Mass Medical Soc
Background Respiratory syncytial virus (RSV), a major cause of illness and death in infants
worldwide, could be prevented by vaccination during pregnancy. The efficacy …

Single-dose nirsevimab for prevention of RSV in preterm infants

MP Griffin, Y Yuan, T Takas… - … England Journal of …, 2020 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is the most common cause of lower
respiratory tract infection in infants, and a need exists for prevention of RSV in healthy …

Bronchiolitis

SR Dalziel, L Haskell, S O'Brien, ML Borland, AC Plint… - The Lancet, 2022 - thelancet.com
Viral bronchiolitis is the most common cause of admission to hospital for infants in high-
income countries. Respiratory syncytial virus accounts for 60–80% of bronchiolitis …

Mortality associated with influenza and respiratory syncytial virus in the US, 1999-2018

CL Hansen, SS Chaves, C Demont… - JAMA Network …, 2022 - jamanetwork.com
Importance Respiratory syncytial virus (RSV) mortality estimates have not been updated
since 2009, and no study has assessed changes in influenza mortality after the 2009 …

Respiratory syncytial virus infection and novel interventions

AC Langedijk, LJ Bont - Nature Reviews Microbiology, 2023 - nature.com
The large global burden of respiratory syncytial virus (RSV) respiratory tract infections in
young children and older adults has gained increased recognition in recent years. Recent …

Heparan sulfate proteoglycans and viral attachment: true receptors or adaptation bias?

V Cagno, ED Tseligka, ST Jones, C Tapparel - Viruses, 2019 - mdpi.com
Heparan sulfate proteoglycans (HSPG) are composed of unbranched, negatively charged
heparan sulfate (HS) polysaccharides attached to a variety of cell surface or extracellular …

Approved antiviral drugs over the past 50 years

E De Clercq, G Li - Clinical microbiology reviews, 2016 - Am Soc Microbiol
Since the first antiviral drug, idoxuridine, was approved in 1963, 90 antiviral drugs
categorized into 13 functional groups have been formally approved for the treatment of the …