[HTML][HTML] Exosomes: Small vesicles with big roles in cancer, vaccine development, and therapeutics

A Thakur, DC Parra, P Motallebnejad, M Brocchi… - Bioactive materials, 2022 - Elsevier
Cancer is a deadly disease that is globally and consistently one of the leading causes of
mortality every year. Despite the availability of chemotherapy, radiotherapy, immunotherapy …

Cancer-derived exosomes: their role in cancer biology and biomarker development

VC Kok, CC Yu - International Journal of Nanomedicine, 2020 - Taylor & Francis
Exosomes are a subset of tiny extracellular vesicles manufactured by all cells and are
present in all body fluids. They are produced actively in tumor cells, which are released and …

The role of lipids in exosome biology and intercellular communication: Function, analytics and applications

J Donoso‐Quezada, S Ayala‐Mar, J González‐Valdez - Traffic, 2021 - Wiley Online Library
Exosomes are extracellular vesicles that in recent years have received special attention for
their regulatory functions in numerous biological processes. Recent evidence suggests a …

Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer

JF Teng, QB Mei, XG Zhou, Y Tang, R Xiong, WQ Qiu… - Cancers, 2020 - mdpi.com
Trillium tschonoskii Maxim (TTM), a traditional Chinese medicine, has been demonstrated to
have a potent anti-tumor effect. Recently, polyphyllin VI (PPVI), a main saponin isolated from …

[HTML][HTML] Extracellular vesicles as mediators of cell-cell communication in ovarian cancer and beyond–A lipids focus

S Rani, A Lai, S Nair, S Sharma, A Handberg… - Cytokine & growth factor …, 2023 - Elsevier
Extracellular vesicles (EVs) are messengers that carry information in the form of proteins,
lipids, and nucleic acids and are not only essential for intercellular communication but also …

Exosomal proteins and lipids as potential biomarkers for lung cancer diagnosis, prognosis, and treatment

MT Hsu, YK Wang, YJ Tseng - Cancers, 2022 - mdpi.com
Simple Summary Exosomes (or extracellular vesicles) are known to mediate intercellular
communication and to transmit molecular signals between cells. Molecules carried by …

Extracellular vesicle-based liquid biopsy biomarkers and their application in precision immuno-oncology

K Asleh, V Dery, C Taylor, M Davey… - Biomarker …, 2023 - Springer
While the field of precision oncology is rapidly expanding and more targeted options are
revolutionizing cancer treatment paradigms, therapeutic resistance particularly to …

Progress on pivotal role and application of exosome in lung cancer carcinogenesis, diagnosis, therapy and prognosis

MY Li, LZ Liu, M Dong - Molecular cancer, 2021 - Springer
Lung cancer is often diagnosed at an advanced stage and has a poor prognosis.
Conventional treatments are not effective for metastatic lung cancer therapy. Although some …

Extracellular vesicles in liquid biopsies: potential for disease diagnosis

J Liu, Y Chen, F Pei, C Zeng, Y Yao… - BioMed Research …, 2021 - Wiley Online Library
Liquid biopsy is conducted through minimally invasive or noninvasive procedures, and the
resulting material can be subjected to genomic, proteomic, and lipidomic analyses for early …

The biological functions and clinical applications of exosomes in lung cancer

R Chen, X Xu, Z Qian, C Zhang, Y Niu, Z Wang… - Cellular and Molecular …, 2019 - Springer
Lung cancer remains the leading cause of cancer-related death worldwide, and the high
incidence rates are worrisome. Exosomes are a class of extracellular vesicles secreted by …