Planarians are members of the Platyhelminthes (flatworms). These animals have evolved a
remarkable stem cell system. A single pluripotent adult stem cell type (“neoblast”) gives rise …

The foundation of the diverse metazoan nervous systems is laid by embryonic patterning
mechanisms, involving the generation and movement of neural progenitors and their …

Abstract Background The freshwater planarian Schmidtea mediterranea has emerged as a
powerful model for studies of regenerative, stem cell, and germ cell biology. Whole-mount in …

Planarian flatworms are a popular system for research into the molecular mechanisms that
enable these complex organisms to regenerate their entire body, including the brain …

Regeneration of complex structures after injury requires dramatic changes in cellular
behavior. Regenerating tissues initiate a program that includes diverse processes such as …

Regarding the humane use of animals in scientific research, invertebrates are often
recommended in toxicological studies.“Freshwater planarians” refers to numerous free-living …

Planarians have a long history in the fields of developmental and regenerative biology.
These animals have also sparked interest in neuroscience due to their neuroanatomy …

Freshwater planarians, famous for their regenerative prowess, have long been recognized
as a valuable in vivo animal model to study the effects of chemical exposure. In this review …

Advances in stem cell biology have led to the derivation of diverse cell types, yet challenges
remain in creating complex tissues and functional organs. Unlike humans, some animals …

As a persistent and widespread toxic organic pollutant in the environment, perfluorooctane
sulfonate (PFOS) has the potential to cause great harm to wildlife. In our study, the effects of …